Prenylated acylphloroglucinols, chipericumins A-D, from Hypericum chinense

  • J Nat Prod. 2012 Mar 23;75(3):484-8. doi: 10.1021/np200741x.
Shuhei Abe  1 ,  Naonobu Tanaka ,  Jun'ichi Kobayashi
Affiliations
  • 1. Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
PMID: 22074257 DOI: 10.1021/np200741x
Abstract

Two new tetracyclic prenylated acylphloroglucinols, chipericumins A (1) and B (2), were isolated from the roots of Hypericum chinense, together with two new tricyclic prenylated acylphloroglucinols, chipericumins C (3) and D (4). Their structures were elucidated by spectroscopic data. Chipericumins A-D (1-4) are prenylated acylphloroglucinols having a spiro skeleton with an acyl group, a methyl group, a C(5) unit, and a monoterpene moiety in common.