Pyronepolyene C-glucosides with NF-κB inhibitory and anti-influenza A viral (H1N1) activities from the sponge-associated fungus Epicoccum sp. JJY40

  • Bioorg Med Chem Lett. 2012 May 1;22(9):3188-90. doi: 10.1016/j.bmcl.2012.03.044.
Jixing Peng  1 ,  Jieying Jiao ,  Jing Li ,  Wei Wang ,  Qianqun Gu ,  Tianjiao Zhu ,  Dehai Li
Affiliations
  • 1. Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
PMID: 22487178 DOI: 10.1016/j.bmcl.2012.03.044
Abstract

A new pyronepolyene C-glucoside, named iso-D8646-2-6 (1) together with the known related compound D8646-2-6 (2), was isolated from the sponge-associated fungus Epicoccum sp. JJY40. They showed NF-κB inhibitory and anti-influenza A viral (H1N1) activities.