Toll-like receptor signaling

  • Cold Spring Harb Perspect Biol. 2013 Jan 1;5(1):a011247. doi: 10.1101/cshperspect.a011247.
Kian-Huat Lim  1 ,  Louis M Staudt
Affiliations
  • 1. Metabolism Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
PMID: 23284045 DOI: 10.1101/cshperspect.a011247
Abstract

Toll-like receptors sense pathogen-associated molecular patterns (e.g., lipopolysaccharides) and trigger gene-expression changes that ultimately eradicate the invading microbes.