Synthetic approaches to the 2011 new drugs

  • Bioorg Med Chem. 2013 Jun 1;21(11):2795-825. doi: 10.1016/j.bmc.2013.02.061.
Hong X Ding  1 ,  Kevin K-C Liu ,  Subas M Sakya ,  Andrew C Flick ,  Christopher J O'Donnell
Affiliations
PMID: 23623674 DOI: 10.1016/j.bmc.2013.02.061
Abstract

New drugs are introduced to the market every year and each represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the synthesis of 26 NCEs that were launched in the world in 2011.