Caging the elephant: selective autophagy tackles giant intracellular protein crystals

  • Mol Cell. 2015 Apr 2;58(1):5-7. doi: 10.1016/j.molcel.2015.03.022.
Sabrina Habisov  1 ,  Vladimir Kirkin  2
Affiliations
  • 1. Merck KGaA, Frankfurter Strasse 250, 64293 Darmstadt, Germany; BMLS Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany.
  • 2. Merck KGaA, Frankfurter Strasse 250, 64293 Darmstadt, Germany. Electronic address: [email protected].
PMID: 25839431 DOI: 10.1016/j.molcel.2015.03.022
Abstract

In this issue of Molecular Cell, Tsutsui et al. (2015) show that in vivo protein crystallization may come in handy not only when solving the structure of a protein, but also when studying molecular mechanisms of selective Autophagy.