Kinsenoside: A Promising Bioactive Compound from Anoectochilus Species

  • Curr Med Sci. 2018 Feb;38(1):11-18. doi: 10.1007/s11596-018-1841-1.
Chang-Xing Qi  1 ,  Qun Zhou  1 ,  Zhou Yuan  1 ,  Zeng-Wei Luo  1 ,  Chong Dai  1 ,  Hu-Cheng Zhu  1 ,  Chun-Mei Chen  1 ,  Yong-Bo Xue  1 ,  Jian-Ping Wang  1 ,  Ya-Fen Wang  1 ,  Ya-Ping Liu  1 ,  Ming Xiang  1 ,  Wei-Guang Sun  1 ,  Jin-Wen Zhang  2 ,  Yong-Hui Zhang  3
Affiliations
  • 1. Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
  • 2. Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. [email protected].
  • 3. Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. [email protected].
PMID: 30074146 DOI: 10.1007/s11596-018-1841-1
Abstract

Kinsenoside is a main active component isolated from Plants of the genus Anoectochilus, and exhibits many biological activities and pharmacological effects, including hepatoprotective, anti-hyperglycemic, anti-hyperliposis, anti-inflammatory, vascular protective and anti-osteoporosis effects and so on, which is contributing to its promising potency in disease treatments. This review aims to recapitulate the pharmacological functions of kinsenoside, as well as its source, extraction, identification, quantitative analysis, pharmacokinetics, synthesis and patent information. The data reported in this work can confirm the therapeutic potential of kinsenoside and provide useful information for further new drug development.

Keywords
Anoectochilus roxburghii; bioactivity; kinsenoside; review; synthesis.
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