The molecular diversity scope of 4-hydroxycoumarin in the synthesis of heterocyclic compounds via multicomponent reactions

  • Mol Divers. 2019 Nov;23(4):1029-1064. doi: 10.1007/s11030-019-09918-7.
Ghodsi Mohammadi Ziarani  1 Razieh Moradi  2 Tahereh Ahmadi  3 Parisa Gholamzadeh  3
Affiliations
  • 1. Department of Chemistry, Alzahra University, Tehran, Iran. [email protected].
  • 2. Department of Chemistry, Alzahra University, Tehran, Iran. [email protected].
  • 3. Department of Chemistry, Alzahra University, Tehran, Iran.
Abstract

4-Hydroxycoumarins are some of the most versatile heterocyclic scaffolds and are frequently applied in the synthesis of various organic compounds. 4-Hydroxycoumarin-based compounds are important among heterocyclic structures due to their biological and pharmaceutical activities. In this study, we provide an overview on the recent applications of 4-hydroxycoumarin in multicomponent reactions for the synthesis of various heterocyclic compounds during the time period of 2015-2018.

Keywords
4-Hydroxycoumarin; Heterocycles; Multicomponent reaction; Synthesis.
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