[Studies on alkaloid constituents of Fritillaria yuminensis]

  • Zhongguo Zhong Yao Za Zhi. 2019 Feb;44(3):495-499. doi: 10.19540/j.cnki.cjcmm.20181121.005.
Jian-Fa Zong  1 ,  Zhu Hu  1 ,  Aisa Hajiakber  2 ,  Chun Lei  1 ,  Yili Abulimiti  2 ,  Ai-Jun Hou  1
Affiliations
  • 1. School of Pharmacy, Fudan University Shanghai 201203, China.
  • 2. Key Laboratory of Plant Resources and Chemistry in Arid Zone and State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences Urumqi 830011, China.
PMID: 30989914 DOI: 10.19540/j.cnki.cjcmm.20181121.005
Abstract

Twelve Alkaloids were isolated from the bulbs of Fritillaria yuminensis by column chromatography over silica gel, ODS, and Sephadex LH-20, as well as RP-HPLC. Their structures were identified mainly by NMR and MS analyses as yubeinine(1), imperialine(2), delavinone(3), tortifoline(4), hupehenizioiside(5), imperialine-β-D-glucoside(6), kuroyurinidine(7), pengbeisine A(8), walujewine A(9), peimisine-3-O-β-D-glucopyranoside(10), solanidine-3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside(11), and solanidine-3-O-α-L-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→4)]-β-D-glucopyranoside(12). Compounds 4-12 were obtained from F. yuminensis for the first time.

Keywords
Fritillaria yuminensis; alkaloids; chemical constituents.
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