RETRACTED: Notoginsenoside R1 protects human renal proximal tubular epithelial cells from lipopolysaccharide-stimulated inflammatory damage by up-regulation of miR-26a

  • Chem Biol Interact. 2019 Aug 1;308:364-371. doi: 10.1016/j.cbi.2019.05.053.
Jinrong Liu  1 Cun Hou  1 Xiaoyuan Chen  2 Lin Wu  3 Xinyue Wang  4
Affiliations
  • 1. Department of Nephrology, Jining No.1 People's Hospital, Jining, 272011, China.
  • 2. Department of Pharmacy, Dongying People's Hospital, Dongying, 257091, China.
  • 3. Department of Trauma and Orthopaedic Surgery, Shengli Oilfield Central Hospital, Dongying, 257034, China.
  • 4. Department of Nephrology, Dongying People's Hospital, Dongying, 257091, China. Electronic address: [email protected].
Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. There were serious questions about the validity of the data contained in these articles: "... the Western blot bands in ... papers are all very regularly spaced and have a smooth appearance in the shape of a dumbbell or tadpole, without any of the usual smudges or stains. All bands are placed on similar looking backgrounds, suggesting they were copy/pasted from Other sources, or computer generated". Based on the latter findings, the Editor-in-Chief requested the authors to provide the raw data. However, the authors were not willing and/or able to fulfil this request and therefore the Editor-in-Chief decided to retract the article. As a consequence the writing in this article misled and deceived reviewers and readers of the journal and thus as a whole represents a gross misuse of the scientific publishing system. The scientific community takes a very strong view on this matter and apologies are offered to readers of the journal that this was not detected during the submission process.

Keywords
Chronic kidney disease; Lipopolysaccharide; MicroRNA-26a; NF-κB pathway; Notoginsenoside R1; Renal proximal tubular epithelial cells.
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