Naturally Occurring Lumazines

  • J Nat Prod. 2019 Jul 26;82(7):2054-2065. doi: 10.1021/acs.jnatprod.9b00351.
Benjamin J Daniels  1 ,  Freda F Li  1 ,  Daniel P Furkert  1  2 ,  Margaret A Brimble  1  2
Affiliations
  • 1. School of Chemical Sciences , The University of Auckland , 23 Symonds Street , Auckland 1010 , New Zealand.
  • 2. Maurice Wilkins Centre for Molecular Biodiscovery , The University of Auckland , 3 Symonds Street , Auckland 1010 , New Zealand.
PMID: 31317731 DOI: 10.1021/acs.jnatprod.9b00351
Abstract

Natural products containing a lumazine motif were first isolated from natural sources in 1940. These natural products are relatively rare, with fewer than 100 lumazines known to occur in Nature. This review discusses the isolation of lumazines, their biological activity, and their biosynthesis, where known.