TEMPO catalyzed oxidative dehydrogenation of hydrazobenzenes to azobenzenes

  • Org Biomol Chem. 2020 May 13;18(18):3471-3474. doi: 10.1039/d0ob00103a.
Haiping Lv  1 ,  Ronibala Devi Laishram ,  Yong Yang ,  Jiayan Li ,  Dandan Xu ,  Yong Zhan ,  Yang Luo ,  Zhimin Su ,  Sagar More ,  Baomin Fan
Affiliations
  • 1. Chongqing Academy of Chinese Materia Medica, Chongqing, 400065, China. [email protected].
PMID: 32319504 DOI: 10.1039/d0ob00103a
Abstract

A metal-free direct oxidative dehydrogenation approach for the synthesis of azobenzenes from hydrazobenzenes has been developed by using TEMPO as an organocatalyst for the first time. The reaction proceeded in open air under mild reaction conditions. A wide range of hydrazobenzenes readily undergo dehydrogenation to give the corresponding azobenzenes in excellent yields.

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