Fungal Bioactive Anthraquinones and Analogues

  • Toxins (Basel). 2020 Nov 12;12(11):714. doi: 10.3390/toxins12110714.
Marco Masi  1 Antonio Evidente  1
Affiliations
  • 1. Dipartimento di Scienze Chimiche, Università di Napoli Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, 80126 Napoli, Italy.
Abstract

This review, covering the literature from 1966 to the present (2020), describes naturally occurring Fungal bioactive Anthraquinones and analogues biosynthesized by the acetate route and concerning several different functionalized carbon skeletons. Hydrocarbons, lipids, sterols, esters, fatty acids, derivatives of Amino acids, and aromatic compounds are metabolites belonging to Other different classes of natural compounds and are generated by the same biosynthetic route. All of them are produced by plant, Microorganisms, and marine organisms. The biological activities of Anthraquinones and analogues comprise phytotoxic, Antibacterial, Antiviral, Anticancer, antitumor, algicide, Antifungal, enzyme inhibiting, immunostimulant, antiplatelet aggregation, cytotoxic, and antiplasmodium activities. The review also covers some practical industrial applications of Anthraquinones.

Keywords
anthraquinones; biological activity; fungi; natural analogues.
Products