E17241 as a Novel ABCA1 (ATP-Binding Cassette Transporter A1) Upregulator Ameliorates Atherosclerosis in Mice

  • Arterioscler Thromb Vasc Biol. 2021 Jun;41(6):e284-e298. doi: 10.1161/ATVBAHA.120.314156.
Yanni Xu (许艳妮)  #  1 ,  Chang Liu (刘畅)  #  1 ,  Xiaowan Han (韩小婉)  #  1  2 ,  Xiaojian Jia (贾晓健)  1 ,  Yongzhen Li (李永臻)  1 ,  Chao Liu (刘超)  1 ,  Ni Li (李霓)  1  2 ,  Lunming Liu (刘伦铭)  1 ,  Peng Liu (刘鹏)  1 ,  Xinhai Jiang (姜新海)  1 ,  Weizhi Wang (王伟志)  1 ,  Xiao Wang (王潇)  1 ,  Yining Li (李依宁)  1 ,  Mingzhu Chen (陈明珠)  1 ,  Jinque Luo (罗金雀)  1 ,  Xuan Zuo (左璇)  1 ,  Jiangxue Han (韩江雪)  1 ,  Li Wang (王丽)  1 ,  Yu Du (杜郁)  1 ,  Yang Xu (徐扬)  1 ,  Jian-Dong Jiang (蒋建东)  1  2 ,  Bin Hong (洪斌)  1 ,  Shuyi Si (司书毅)  1
Affiliations
  • 1. NHC Key Laboratory of Biotechnology of Antibiotics, National Center for New Microbial Drug Screening, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS&PUMC), Beijing, China (Y.X., C.L., X.H., X. Jia, Y.L., C.L., N.L., L.L., P.L., X. Jiang, W.W., X.W., Y.L., M.C., J.L., X.Z., J.H., L.W., Y.D., Y.X., J.-D.J., B.H., S.S.).
  • 2. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, CAMS&PUMC, Beijing, China (X.H., N.L., J.-D.J.).
  • # Contributed equally.
PMID: 33441025 DOI: 10.1161/ATVBAHA.120.314156
Abstract

[Figure: see text].

Keywords
atherosclerosis; cardiovascular disease; cholesterol; drug discovery; macrophages.
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