2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. E17241

E17241 is an inducer of the expression of ABCA1 that increases the protein levels of ABCA1 in RAW 264.7 macrophages. E17241 is also an agonist of peroxisome proliferator-activated receptors (PPARs ). E17241 decreases plasma glucose levels and body weight in KKAy diabetic mice fed a high-fat and high-glucose (HFHG) diet.

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E17241

E17241 Chemical Structure

CAS No. : 1060968-92-4

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E17241 Related Antibodies

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Description

E17241 is an inducer of the expression of ABCA1 that increases the protein levels of ABCA1 in RAW 264.7 macrophages. E17241 is also an agonist of peroxisome proliferator-activated receptors (PPARs ). E17241 decreases plasma glucose levels and body weight in KKAy diabetic mice fed a high-fat and high-glucose (HFHG) diet[1][2].

Molecular Weight

318.41

Formula

C15H14N2O2S2
CAS No.
Appearance

Powder

Color

Off-white to light yellow

SMILES

O=C(C1=CC=C(C2SCCS2)C=C1)NC3=NC=CC=C3O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (39.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1406 mL 15.7030 mL 31.4060 mL
5 mM 0.6281 mL 3.1406 mL 6.2812 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1406 mL 15.7030 mL 31.4060 mL 78.5151 mL
5 mM 0.6281 mL 3.1406 mL 6.2812 mL 15.7030 mL
10 mM 0.3141 mL 1.5703 mL 3.1406 mL 7.8515 mL
15 mM 0.2094 mL 1.0469 mL 2.0937 mL 5.2343 mL
20 mM 0.1570 mL 0.7852 mL 1.5703 mL 3.9258 mL
25 mM 0.1256 mL 0.6281 mL 1.2562 mL 3.1406 mL
30 mM 0.1047 mL 0.5234 mL 1.0469 mL 2.6172 mL
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E17241 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E172411060968-92-4E 17241E-17241PPARPeroxisome proliferator-activated receptorsABCA1RAW 264.7 macrophagesPPARsInhibitorinhibitorinhibit

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