Dual blocking of PI3K and mTOR signaling by DHW-221, a novel benzimidazole derivative, exerts antitumor activity in human non-small cell lung cancer

  • Clin Transl Med. 2021 Sep;11(9):e514. doi: 10.1002/ctm2.514.
Xiaochun Qin  1 ,  Mingyue Liu  1 ,  Yuting Wu  1 ,  Shu Wang  1 ,  Siheng Lian  1 ,  Hui Jia  2 ,  Qiong Wu  2 ,  Huaiwei Ding  3 ,  Qingchun Zhao  1  2
Affiliations
  • 1. Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang, China.
  • 2. Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, China.
  • 3. Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
PMID: 34586727 DOI: 10.1002/ctm2.514
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