Inosamycin, a complex of new aminoglycoside antibiotics. II. Structure determination

  • J Antibiot (Tokyo). 1985 Oct;38(10):1313-21. doi: 10.7164/antibiotics.38.1313.
M Tsunakawa ,  M Hanada ,  H Tsukiura ,  M Konishi ,  H Kawaguchi
PMID: 4066487 DOI: 10.7164/antibiotics.38.1313
Abstract

Structures of the new aminocyclitol Antibiotics, inosamycins A, B, C, D and E, have been determined by a combination of chemical degradation and spectroscopic studies. They are structurally related to neomycin, paromomycin and ribostamycin but differ in that all the inosamycin components contain 2-deoxy-scyllo-inosamine in place of 2-deoxystreptamine in the known Aminoglycoside antibiotics.

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