Pain management beyond opioids: a β-arrestin2-biased allosteric GPCR modulator opens new avenues for drug development

  • Signal Transduct Target Ther. 2025 Aug 27;10(1):264. doi: 10.1038/s41392-025-02361-1.
Eline Pottie  #  1 ,  Sophie A M Steinmüller  #  2 ,  Michael Decker  3
Affiliations
  • 1. Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
  • 2. School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen Foresterhill, Aberdeen, UK.
  • 3. Pharmazeutische und Medizinische Chemie, Institut für Pharmazie und Lebensmittelchemie, Julius-Maximilians-Universität Würzburg (JMU), Würzburg, Germany. [email protected].
  • # Contributed equally.
PMID: 40858534 DOI: 10.1038/s41392-025-02361-1
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