Neuroprotective effect of sinomenine on parkinson's disease through NLRP3/Caspase-1/GSDMD pathway-mediated pyroptosis inhibition

  • Metab Brain Dis. 2026 Jan 20;41(1):22. doi: 10.1007/s11011-025-01784-7.
Xi Bao  1 ,  JingCai Xu  1 ,  Jia Zhou  1 ,  Lin Huang  2 ,  HaiChang Li  2 ,  Yun Huang  3
Affiliations
  • 1. Department of Geriatrics, Hangzhou Hospital of Traditional Chinese Medicine, No. 453, Stadium Road, Xihu District, Hangzhou, Zhejiang, 310007, China.
  • 2. School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
  • 3. Department of Chinese Medicine Gynecology, Hangzhou Hospital of Traditional Chinese Medicine, No. 453, Stadium Road, Xihu District, Hangzhou, Zhejiang, 310007, China. [email protected].
PMID: 41557055 DOI: 10.1007/s11011-025-01784-7
Keywords
NLRP3; Neuroprotective effect; Parkinson’s disease; Pyroptosis; Sinomenine.
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