On the role of cholesterol, vitamin D, lumisterol, and tachysterol signaling in psoriasis

  • J Invest Dermatol. 2026 Apr;146(4):887-889. doi: 10.1016/j.jid.2026.01.005.
Andrzej T Slominski  1 ,  Robert C Tuckey  2 ,  Radomir M Slominski  3 ,  Michael F Holick  4 ,  Anton M Jetten  5
Affiliations
  • 1. Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA; Cancer Chemoprevention Program, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, USA; Birmingham VA Medical Center, Birmingham, Alabama, USA. Electronic address: [email protected].
  • 2. School of Molecular Sciences, The University of Western Australia, Perth, Australia.
  • 3. Division of Immunology/Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
  • 4. Department of Medicine, Boston University Chobonian & Avedisian School of Medicine, Boston, Massachusetts, USA.
  • 5. Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.
PMID: 41718524 DOI: 10.1016/j.jid.2026.01.005
Keywords
7-Dehydrocholesterol; 7-Dehydrodesmosterol; Nuclear receptors; Secosteroids; UVB radiation.
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