A high-content phenotypic screen identifies luteolin as a repurposed drug to reduce pyruvate dehydrogenase phosphorylation and enhance energy production in CMTX6 cell models

Gonzalo Perez-Siles  ^{1  2} ,  Masahiro Nishide  ² ,  Melina Ellis  ¹ ,  Richard M Wynn  ³ ,  Gauri Shishodia  ^{1  3} ,  Steve Vucic  ⁴ ,  Marina L Kennerson  ^{1  2  5}