Apparent gastrointestinal origin of cis-4-hydroxycyclohexanecarboxylic acid

  • Clin Chim Acta. 1983 Aug 15;132(2):205-8. doi: 10.1016/0009-8981(83)90249-8.
J B Kronick ,  O A Mamer ,  J Montgomery ,  C R Scriver
PMID: 6616875 DOI: 10.1016/0009-8981(83)90249-8
Abstract

We identified by gas chromatography-mass spectrometry the unusual substance cis-4-hydroxycyclohexanecarboxylic acid (4-HCH) in the urine of a child. Urinary excretion of 4-HCH and intestinal bacteria were both suppressed by neomycin treatment. We propose that 4-HCH is a by-product of Bacterial metabolism.

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