Antioxidative activity of hop bitter acids and their analogues

  • Biosci Biotechnol Biochem. 1995 Apr;59(4):740-2. doi: 10.1271/bbb.59.740.
M Tagashira  1 ,  M Watanabe ,  N Uemitsu
Affiliations
  • 1. Central Research Laboratories, Asahi Breweries Ltd., Tokyo, Japan.
PMID: 7772843 DOI: 10.1271/bbb.59.740
Abstract

Hop bitter acids, humulones (1) and lupulones (2), were shown to have potent DPPH radical scavenging activity (RSA) and lipid peroxidation inhibitory activity (LIA). Furthermore, 5-acetyl lupulones (3) and 4-methyl lupulones (4) had more potent LIA than native lupulones but no RSA. This result indicates that the beta, beta'-triketone moiety of the lupulones has LIA.

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