Identification of pheophorbide a and its related compounds as possible anti-tumor promoters in the leaves of Neptunia oleracea

  • Biosci Biotechnol Biochem. 1996 Jun;60(6):1028-30. doi: 10.1271/bbb.60.1028.
Y Nakamura  1 ,  A Murakami ,  K Koshimizu ,  H Ohigashi
Affiliations
  • 1. Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Japan.
PMID: 8695903 DOI: 10.1271/bbb.60.1028
Abstract

Six chlorophyll-related compounds isolated from leaves of Neptunia oleracea (Leguminosae) inhibited the activation of tumor promoter-induced Epstein-Barr virus (EBV). Photo-irradiation of pheophorbide a, the major active constituent, did not enhance this inhibitory activity, and thus ruled out any photosensitizing effect playing the major role.

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