UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp. 517-02. I. Fermentation, isolation, and biological properties

  • J Antibiot (Tokyo). 1996 Jul;49(7):639-43. doi: 10.7164/antibiotics.49.639.
M Ueki  1 ,  K Abe ,  M Hanafi ,  K Shibata ,  T Tanaka ,  M Taniguchi
Affiliations
  • 1. Faculty of Science, Osaka City University, Japan.
PMID: 8784423 DOI: 10.7164/antibiotics.49.639
Abstract

Novel antifungal Antibiotics, UK-2A, B and a mixture of C and D, were obtained from the mycelial cake of Streptomyces sp. 517-02. All of the UK-2 compounds were similar in structure to antimycin A. The Antifungal activities of UK-2 compounds were as strong as that of antimycin A. However, the UK-2 compounds demonstrated weak cytotoxicity compared to antimycin A.

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