Antiseptic myramistin possesses the strong anti-HIV properties

  • Mikrobiol Z. 1996 Sep-Oct;58(5):90-2.
Iu L Kryvorutchenko  1 ,  Iu S Kryvosheïn ,  I B Andronovs'ka ,  S S Marennykova ,  L H Stepanova ,  D N Nosyk ,  L B Kalnina ,  A P Rud'ko
Affiliations
  • 1. Department of Microbiology, Crimean Medical Institute, Simferopol.
PMID: 8993062
Abstract

The anti-HIV properties of cation detergent myramistin were studied. The dose-dependent slowing down both of the HIV antigens accumulation in supernatants and the virus-dependent cell death was shown at myramistin concentrations 30 micrograms/ml and 50 micrograms/ml in the MT-4 cell line. Simultaneous addition of the trace amount of the detergents and HIV-1 to the cells of Jurkat-tat line did not stimulate the HIV p24 production for 4 days of the experiment.

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