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Cat. No.: HY-115853B

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Pyclen sulfate

Pyclen sulfate forms kinetically and thermodynamically stable nine-coordinate Ln (III) complexes, as well as Mn (II)-based MRI contrast agents. Pyclen-Based Mn(II) Complexes can be used for liver-specific MRI.

For research use only. We do not sell to patients.

CAS No.: 129135-03-1
Formula: C₁₁H₂₀N₄O₄S
Molecular Weight:304.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pyclen sulfate Chemical Structure

CAS No.: 129135-03-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
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Biological Activity

Description

In Vitro

Pyclen can form stable, highly luminescent lanthanide (III) complexes, which serve as one- and two-photon biological probes. These complexes stain living human breast cancer cells, exhibit no significant toxicity in the living Danio rerio (zebrafish) model, and enable high-quality in vivo two-photon microscopy imaging^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 129135-03-1
Molecular Weight 304.37
Formula C₁₁H₂₀N₄O₄S
SMILES

O=S(=O)(O)O.N=1C2=CC=CC1CNCCNCCNC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hamon N, et al. Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications. J Am Chem Soc. 2020 Jun 3;142(22):10184-10197. [Content Brief]

[2]. Hall RC, et al. Manganese(II) EOB-Pyclen Diacetate for Liver-Specific MRI. ACS Appl Bio Mater. 2022;5(2):451-458. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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