Pyclen sulfate
Pyclen sulfate forms kinetically and thermodynamically stable nine-coordinate Ln (III) complexes, as well as Mn (II)-based MRI contrast agents. Pyclen-Based Mn(II) Complexes can be used for liver-specific MRI.
For research use only. We do not sell to patients.
- CAS No.: 129135-03-1
- Formula: C11H20N4O4S
- Molecular Weight:304.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Pyclen can form stable, highly luminescent lanthanide (III) complexes, which serve as one- and two-photon biological probes. These complexes stain living human breast cancer cells, exhibit no significant toxicity in the living Danio rerio (zebrafish) model, and enable high-quality in vivo two-photon microscopy imaging[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 129135-03-1
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Molecular Weight 304.37
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Formula C11H20N4O4S
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SMILES
O=S(=O)(O)O.N=1C2=CC=CC1CNCCNCCNC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hamon N, et al. Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications. J Am Chem Soc. 2020 Jun 3;142(22):10184-10197. [Content Brief]
[2]. Hall RC, et al. Manganese(II) EOB-Pyclen Diacetate for Liver-Specific MRI. ACS Appl Bio Mater. 2022;5(2):451-458. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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