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Cat. No.: HY-N12120

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Retrofractamide A

Name: Retrofractamide A
Brand: MedChemExpress
SKU: HY-N12120
Price: 450.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Retrofractamide A is an amide constituent that can be isolated from the fruit of Piper chaba. Retrofractamide A promotes adipogenesis in 3T3-L1 cells.

For research use only. We do not sell to patients.

CAS No.: 94079-67-1
Formula: C₂₀H₂₅NO₃
Molecular Weight:327.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

$Retrofractamide A Chemical Structure$

Retrofractamide A Chemical Structure

CAS No.: 94079-67-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Retrofractamide A is an amide constituent that can be isolated from the fruit of Piper chaba. Retrofractamide A promotes adipogenesis in 3T3-L1 cells^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	>20 μM Compound: 2a	Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay	[PMID: 21745740]
Hepatocyte	IC₅₀	21 μM Compound: 26	Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cytotoxicity after 20 hrs by MTT assay relative to untreated control Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cytotoxicity after 20 hrs by MTT assay relative to untreated control	[PMID: 19775895]

Chemical Information

CAS No. 94079-67-1
Molecular Weight 327.42
Formula C₂₀H₂₅NO₃
SMILES

CC(C)CNC(/C=C/C=C/CC/C=C/C1=CC=C(OCO2)C2=C1)=O
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mourad AA, et al. Adipogenetic effects of retrofractamide A derivatives in 3T3-L1 cells. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4813-6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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