Rhodady C10
Rhodady C10 (Compound C10) is a dynamin I GTPase inhibitor. Rhodady C10 blocks receptor-mediated endocytosis (IC50: 7 μM). Dynamin is involved in clathrin-independent endocytosis, phagocytosis, and caveolae internalization.
For research use only. We do not sell to patients.
- CAS No.: 1367579-04-1
- Formula: C17H22N2O2S2
- Molecular Weight:350.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U2OS | IC50 |
7 μM
Compound: C10
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Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas red-Tf addition measured after 8 mins by receptor-mediated endocytosis assay
Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas red-Tf addition measured after 8 mins by receptor-mediated endocytosis assay
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[PMID: 24900478] |
Chemical Information
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CAS No. 1367579-04-1
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Molecular Weight 350.50
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Formula C17H22N2O2S2
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SMILES
O=C1/C(SC(N1CC)=S)=C/C2=CC=C(C=C2)OCCCN(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Rhodady C10 Related Classifications
HY-164290 Related Classifications
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