2. Natural Products
  3. Plants Flavonoids
  4. Selaginellaceae Biflavones
  5. Selaginella uncinata (Desv.) Spring
  6. Robustaflavone 4′-methyl ether

Robustaflavone 4′-methyl ether is a biflavonoid compound that can be isolated from the whole plant of Selaginella gracillima. Robustaflavone 4′-methyl ether inhibits the growth of cancer cells. Robustaflavone 4′-methyl ether can be used in the research of EBV-transformed B-cell carcinoma and lung cancer.

For research use only. We do not sell to patients.

Robustaflavone 4′-methyl ether

Robustaflavone 4′-methyl ether Chemical Structure

CAS No. : 275365-36-1

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Robustaflavone 4′-methyl ether Related Antibodies

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Description

Robustaflavone 4′-methyl ether is a biflavonoid compound that can be isolated from the whole plant of Selaginella gracillima. Robustaflavone 4′-methyl ether inhibits the growth of cancer cells. Robustaflavone 4′-methyl ether can be used in the research of EBV-transformed B-cell carcinoma and lung cancer[1].

In Vitro

Robustaflavone 4′-methyl ether (Compound 1) (12.5-100 μM; 3 days) significantly inhibits the growth of Raji and Calu-1 cell lines in a concentration-dependent manner, but exhibits only extremely weak or even no inhibitory activity against K562, HeLa, Vero and Wish cell lines; at the concentration of 100 μM, its maximum inhibition rate reaches 98.4 % for Raji cells and 100 % for Calu-1 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Robustaflavone 4′-methyl ether Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: Raji, Calu-1, K562, HeLa, Vero, Wish cell lines
Concentration: 12.5, 25, 50, 100 μM
Incubation Time: 3 days
Result: Inhibited Raji cell growth by 98.4% and Calu-1 cell growth by 100% at 100 μM.
Inhibited Raji cell growth by 68.5% and Calu-1 cell growth by 77.9% at 50 μM.
Inhibited Raji cell growth by 60.7% and Calu-1 cell growth by 44.6% at 25 μM.
Inhibited Raji cell growth by 34.2% and Calu-1 cell growth by 42.6% at 12.5 μM.
Molecular Weight

552.48

Formula

C31H20O10
CAS No.
SMILES

O=C1C=C(C2=CC(C3=C(C=C4OC(C5=CC=C(O)C=C5)=CC(C4=C3O)=O)O)=C(OC)C=C2)OC6=C1C(O)=CC(O)=C6
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Robustaflavone 4′-methyl ether Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Robustaflavone 4′-methyl ether275365-36-1OthersbiflavonoidEBV-transformed B-cell carcinoma and lung cancerRaji cellsCalu-1 cellsK562 cellsHeLa cellsVerocellsInhibitorinhibitorinhibit

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