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S-Hydroprene is an insecticide. S-Hydroprene prolongs larval and pupa durations, disrupts larval development, suppresses pupation, and exhibits larvicidal activity against Culex quinquefasciatus and Blatta orientalis.

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S-Hydroprene

S-Hydroprene Chemical Structure

CAS No. : 65733-18-8

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Description

S-Hydroprene is an insecticide. S-Hydroprene prolongs larval and pupa durations, disrupts larval development, suppresses pupation, and exhibits larvicidal activity against Culex quinquefasciatus and Blatta orientalis[1][2].

In Vivo

S-Hydroprene (0.1-0.6 mL/L (125 mg/mL); aquatic exposure; 24 h) exhibits low larvicidal activity against Culex quinquefasciatus larvae (maximum 9.33% mortality at 0.6 mL/L, LC50 = 0.020 mL/L) but causes significant, dose-dependent delays in larval development, reduced adult emergence, and morphological abnormalities, supporting its use as an insect growth regulator for vector control[1].
S-Hydroprene (18-100 mg/m2; direct contact or vapour exposure; continuous exposure; 44 days) does not significantly reduce B. orientalis ootheca hatching rate or nymph emergence per hatched ootheca[2].
S-Hydroprene (18-100 mg/m2; direct contact or vapour exposure; continuous exposure; 44 days) at 18 mg/m2 and 100 mg/m2 direct contact induces dose-dependent deformity in A. hagenowii offspring, while 100 mg/m2 vapour exposure causes no deformity[2].
S-Hydroprene (18-100 mg/m2; direct contact or vapour exposure; parental exposure) results in normal F1 A. hagenowii females from all treatments maintaining reproductive viability comparable to parental generations, while deformed F1 females from 100 mg/m2 direct contact show significantly reduced host attack rate, fecundity, and survival[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Culex quinquefasciatus larvae[1]
Dosage: 0.1 mL/L, 0.2 mL/L, 0.3 mL/L, 0.4 mL/L, 0.5 mL/L, 0.6 mL/L (125 mg/mL)
Administration: aquatic exposure; 24 h
Result: Exhibited larval mortality rates of 4.67% (0.1 mL/L), 4.67% (0.2 mL/L), 5.33% (0.3 mL/L), 3.33% (0.4 mL/L), 5.33% (0.5 mL/L), and 9.33% (0.6 mL/L) at 24 h.
Showed a significant concentration-dependent effect on mortality, with only the 0.6 mL/L concentration showing a statistically significant difference from the control.
Had a calculated median lethal concentration (LC50) of 0.020 mL/L.
Caused dose-dependent prolongation of larval development, with larval stage durations of 6.80 days (0.1 mL/L), 8.20 days (0.2 mL/L), 8.80 days (0.3 mL/L), 10.00 days (0.4 mL/L), 10.20 days (0.5 mL/L), and 11.20 days (0.6 mL/L) compared to 6.00 days in controls.
Reduced adult emergence rates to 57% (0.1 mL/L, 0.2 mL/L), 31% (0.3 mL/L), 29% (0.4 mL/L), 24% (0.5 mL/L), and 19% (0.6 mL/L) compared to 68% in controls.
Induced morphological abnormalities in larvae (including deformed heads, thoraxes, abdomens, shrunken body parts, and disengaged body parts) and produced larval-pupal intermediates, with no pupal deformities observed.
Animal Model: laboratory strain (originally from Texas A & M University, reared on B. orientalis)[2]
Dosage: 18 mg/m2 (direct contact); 100 mg/m2 (direct contact); 100 mg/m2 (vapour exposure)
Administration: direct contact; continuous exposure; 44 days; vapour exposure; continuous exposure; 44 days
Result: Induced 11.6% offspring deformity (13.8% males, 10.2% females) at 18 mg/m2 direct contact.
Induced 33.3% offspring deformity (39.6% males, 31.7% females) at 100 mg/m2 direct contact.
Induced 0% offspring deformity at 100 mg/m2 vapour exposure.
Shortened parasitoid developmental time significantly compared to controls.
Shifted sex ratio to female bias (1.5:1 at 18 mg/m2 direct contact; 3.9:1 at 100 mg/m2 direct contact; 3.2:1 at 100 mg/m2 vapour exposure).
Showed no significant reduction in adult female parasitoid host attack rate or fecundity.
Showed significantly higher deformity rates in 100 mg/m2 direct contact than 18 mg/m2 direct contact.
Showed significantly higher male deformity than female deformity in both direct contact treatments.
Molecular Weight

266.43

Formula

C17H30O2
CAS No.
SMILES

C(=C(/C=C/C[C@H](CCCC(C)C)C)\C)\C(OCC)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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S-Hydroprene Related Classifications

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Keywords:

S-Hydroprene65733-18-8InsecticideinsecticideInhibitorinhibitorinhibit

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