S-Hydroprene
S-Hydroprene is an insecticide. S-Hydroprene prolongs larval and pupa durations, disrupts larval development, suppresses pupation, and exhibits larvicidal activity against Culex quinquefasciatus and Blatta orientalis.
For research use only. We do not sell to patients.
- CAS No.: 65733-18-8
- Formula: C17H30O2
- Molecular Weight:266.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
S-Hydroprene (18-100 mg/m2; direct contact or vapour exposure; continuous exposure; 44 days) does not significantly reduce B. orientalis ootheca hatching rate or nymph emergence per hatched ootheca[2].
S-Hydroprene (18-100 mg/m2; direct contact or vapour exposure; continuous exposure; 44 days) at 18 mg/m2 and 100 mg/m2 direct contact induces dose-dependent deformity in A. hagenowii offspring, while 100 mg/m2 vapour exposure causes no deformity[2].
S-Hydroprene (18-100 mg/m2; direct contact or vapour exposure; parental exposure) results in normal F1 A. hagenowii females from all treatments maintaining reproductive viability comparable to parental generations, while deformed F1 females from 100 mg/m2 direct contact show significantly reduced host attack rate, fecundity, and survival[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Culex quinquefasciatus larvae[1]
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Dosage:0.1 mL/L, 0.2 mL/L, 0.3 mL/L, 0.4 mL/L, 0.5 mL/L, 0.6 mL/L (125 mg/mL)
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Administration:aquatic exposure; 24 h
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Result:Exhibited larval mortality rates of 4.67% (0.1 mL/L), 4.67% (0.2 mL/L), 5.33% (0.3 mL/L), 3.33% (0.4 mL/L), 5.33% (0.5 mL/L), and 9.33% (0.6 mL/L) at 24 h.
Showed a significant concentration-dependent effect on mortality, with only the 0.6 mL/L concentration showing a statistically significant difference from the control.
Had a calculated median lethal concentration (LC50) of 0.020 mL/L.
Caused dose-dependent prolongation of larval development, with larval stage durations of 6.80 days (0.1 mL/L), 8.20 days (0.2 mL/L), 8.80 days (0.3 mL/L), 10.00 days (0.4 mL/L), 10.20 days (0.5 mL/L), and 11.20 days (0.6 mL/L) compared to 6.00 days in controls.
Reduced adult emergence rates to 57% (0.1 mL/L, 0.2 mL/L), 31% (0.3 mL/L), 29% (0.4 mL/L), 24% (0.5 mL/L), and 19% (0.6 mL/L) compared to 68% in controls.
Induced morphological abnormalities in larvae (including deformed heads, thoraxes, abdomens, shrunken body parts, and disengaged body parts) and produced larval-pupal intermediates, with no pupal deformities observed.
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Animal Model:laboratory strain (originally from Texas A & M University, reared on B. orientalis)[2]
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Dosage:18 mg/m2 (direct contact); 100 mg/m2 (direct contact); 100 mg/m2 (vapour exposure)
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Administration:direct contact; continuous exposure; 44 days; vapour exposure; continuous exposure; 44 days
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Result:Induced 11.6% offspring deformity (13.8% males, 10.2% females) at 18 mg/m2 direct contact.
Induced 33.3% offspring deformity (39.6% males, 31.7% females) at 100 mg/m2 direct contact.
Induced 0% offspring deformity at 100 mg/m2 vapour exposure.
Shortened parasitoid developmental time significantly compared to controls.
Shifted sex ratio to female bias (1.5:1 at 18 mg/m2 direct contact; 3.9:1 at 100 mg/m2 direct contact; 3.2:1 at 100 mg/m2 vapour exposure).
Showed no significant reduction in adult female parasitoid host attack rate or fecundity.
Showed significantly higher deformity rates in 100 mg/m2 direct contact than 18 mg/m2 direct contact.
Showed significantly higher male deformity than female deformity in both direct contact treatments.
Chemical Information
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CAS No. 65733-18-8
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Molecular Weight 266.43
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Formula C17H30O2
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SMILES
C(=C(/C=C/C[C@H](CCCC(C)C)C)\C)\C(OCC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)