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Cat. No.: HY-177127

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Satoprodil

Satoprodil (example 2) is a potent N-methyl-D-aspartate (NMDA) receptor negative allosteric modulator with an IC₅₀ value of 123 nM for NR2B.

For research use only. We do not sell to patients.

CAS No.: 2416269-15-1
Formula: C₁₈H₂₁FN₄O₃
Molecular Weight:360.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Satoprodil Chemical Structure

CAS No.: 2416269-15-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Satoprodil (example 2) is a potent N-methyl-D-aspartate (NMDA) receptor negative allosteric modulator with an IC₅₀ value of 123 nM for NR2B^[1]^[2].

IC₅₀ & Target

NMDA NR2B^[1]

All iGluR Isoforms :

Chemical Information

CAS No. 2416269-15-1
Molecular Weight 360.38
Formula C₁₈H₂₁FN₄O₃
SMILES

CC1=CC(F)=C(OC2=CN=C(CN3CCO[C@@H](C3)C(NC)=O)C=N2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Riccardo Giovannini, et al. 4-pyrazin-2-ylmethyl-morpholine derivatives and the use thereof as medicament. WO2020079039A1.

[2]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Satoprodil

All iGluR Isoforms