Scr-MyomP1 peptide
Scr-MyomP1 peptide is a scrambled peptide derived from the Myomerger protein. Scr-MyomP1 peptide can be conjugated to the surface of lipid nanoparticles and serves as a negative control to verify whether the skeletal muscle targeting effect of MyomP1-modified LNPs is sequence-dependent. Scr-MyomP1-modified mRNA-LNPs do not exhibit skeletal muscle targeting tropism. Scr-MyomP1 peptide can serve as a scrambled negative control for MyomP1.
For research use only. We do not sell to patients.
- Formula: C82H148N30O17
- Molecular Weight:1826.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Scr-MyomP1 peptide is conjugated to mRNA-LNP via DSPE-PEG (2000)-DBCO using the post-insertion method to construct a negative control formulation (mRNA-Scr-MyomP1-LNP), which, compared with unmodified mRNA-LNP, fails to specifically enhance luciferase transfection efficiency in mouse C2C12 myoblasts and myotubes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1826.24
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Formula C82H148N30O17
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Sequence
Ala-Pro-Leu-His-Arg-Gln-Leu-Arg-Leu-Arg-Ala-Leu-Leu-Arg-Leu
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Sequence Shortening
APLHRQLRLRALLRL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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RNA extraction experimental
By lysing cells, releasing RNA, and removing impurities such as proteins and DNA, high-purity RNA products are finally obtained. The commonly used traditional method is the guanidine isothiocyanate/phenol/chloroform method (Trizol), which is suitable for a variety of animal materials including animal tissues, microorganisms, cultured cells, etc., and most plant materials.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Scr-MyomP1 peptide Related Classifications
HY-P12363A Related Classifications
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