SDKPDMAEIEKFDKSK

Name: SDKPDMAEIEKFDKSK
Brand: MedChemExpress
SKU: HY-P3301
Rating: 4.5 (1 reviews)

Cat. No.: HY-P3301 Purity: 99.80%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

SDKPDMAEIEKFDKSK is a peptide derived from thymosin β4 (Tβ4).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

SDKPDMAEIEKFDKSK Chemical Structure

CAS No. : 1339864-27-5

Size	Price	Stock	Quantity
1 mg	USD 220	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 530	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 850	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

SDKPDMAEIEKFDKSK is a peptide derived from thymosin β4 (Tβ4)^[1].

In Vitro

Thymosin β4 (Tβ4) is a 43 amino acid polypeptide that belongs to a large family of highly conserved, small biologically active molecules. Thymosin β4 (Tβ4) inhibits PDGF-BB-induced fibrogenesis, proliferation and migration of HSC by blocking Akt phosphorylation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1868.07

Formula

C₈₀H₁₃₀N₂₀O₂₉S

CAS No.

1339864-27-5

Appearance

Solid

Color

White to off-white

Sequence Shortening

SDKPDMAEIEKFDKSK

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (53.53 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.5353 mL	2.6766 mL	5.3531 mL
5 mM	0.1071 mL	0.5353 mL	1.0706 mL
10 mM	0.0535 mL	0.2677 mL	0.5353 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (53.53 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.80%

Select Batch:

Data Sheet (270 KB) SDS (252 KB)

COA (249 KB) LCMS (255 KB) Elemental Analysis Report (108 KB)

Handling Instructions (2659 KB)

References

[1]. Shah R, et al. Thymosin β4 inhibits PDGF-BB induced activation, proliferation, and migration of human hepatic stellate cells via its actin-binding domain. Expert Opin Biol Ther. 2018;18(sup1):177-184. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.5353 mL	2.6766 mL	5.3531 mL	13.3828 mL
	5 mM	0.1071 mL	0.5353 mL	1.0706 mL	2.6766 mL
	10 mM	0.0535 mL	0.2677 mL	0.5353 mL	1.3383 mL
	15 mM	0.0357 mL	0.1784 mL	0.3569 mL	0.8922 mL
	20 mM	0.0268 mL	0.1338 mL	0.2677 mL	0.6691 mL
	25 mM	0.0214 mL	0.1071 mL	0.2141 mL	0.5353 mL
	30 mM	0.0178 mL	0.0892 mL	0.1784 mL	0.4461 mL
	40 mM	0.0134 mL	0.0669 mL	0.1338 mL	0.3346 mL
	50 mM	0.0107 mL	0.0535 mL	0.1071 mL	0.2677 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SDKPDMAEIEKFDKSK1339864-27-5OthersInhibitorinhibitorinhibit

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SDKPDMAEIEKFDKSK

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