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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
275 Results for "
d18
" in MedChemExpress (MCE) Product Catalog:
Products (275)
275 Results for "d18" in MCE Product Catalog:
Cat. No.: HY-Y1155S
CAS No.: 51219-90-0
Cat. No.: HY-B2015S
CAS No.: 1189903-75-0
Cat. No.: HY-128395
CAS No.: 917104-47-3
Synonyms: C20-DHSM; DHSM (d18:0/20:0)
Target:
Research Areas:
C20-Dihydrosphingomyelin (C20-DHSM; DHSM (d18:0/20:0)) is a saturated form of Sphingomyelin (HY-113498). C20-Dihydrosphingomyelin is a secondary component of most cell sphingolipids and its levels significantly decrease after intermittent fasting during Ramadan. C20-Dihydrosphingomyelin can be used for the development of liposome reagents .
Cat. No.: HY-W015829S
CAS No.: 1398065-52-5
Synonyms: Tetramethylpropylenediamine-d18
Cat. No.: HY-N10634
CAS No.: 74365-77-8
Synonyms: C16 Glucosyl(β) Ceramide (d18:1/16:0)
Cat. No.: HY-N10634S
CAS No.: 71924-12-4
Synonyms: N-ω-CD3-Hexadecaoyl-glucopsychosie; GluCe(d18:1/16:0-d3); Glucosylceamide-d3 (d18:1/16:0-d3)
Cat. No.: HY-158657
CAS No.: 1823032-02-5
Target:
Research Areas:
3-Keto-C12-dihydrosphingosine hydrochloride is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0) .
Synonyms: N-Behenoyl-D-erythro-sphingosine; C22-Ceramide; Cer d18:1/22:0
Target:
Research Areas:
C22-Ceramide (d18:1/22:0) (N-Behenoyl-D-erythro-sphingosine) is an ultra-long-chain ceramide containing a C22:0 behenoyl acyl chain. C22-Ceramide can be glycosylated via CGT-3 to form C22 glucosylceramide (C22 GlcCer), which in turn maintains clathrin membrane localization and lysosomal homeostasis, inhibits TOR signaling and promotes SKN-1 activation, thereby enhancing oxidative stress resistance and extending the lifespan of C. elegans. C22-Ceramide can be used in research on cardiometabolic diseases such as type 2 diabetes, obesity, dyslipidemia, coronary artery disease and thin-cap fibroatheroma (TCFA), as well as oxidative stress and aging-related studies .
Cat. No.: HY-152017S
CAS No.: 2692623-80-4
Target:
Research Areas:
C18 Globotriaosylceramide-d3 is deuterium labeled Gb3(18:1/18:0). Gb3(18:1/18:0) (C18 Globotriaosylceramide (d18:1/18:0)) is an ester product .
Category:
Alkaloids Neurological Disease Other Alkaloids Endogenous metabolite Disease Research Fields Cancer
Target:
Cat. No.: HY-139062
CAS No.: 486991-52-0
Synonyms: C6 Ceramide (d18:1/6:0) Urea; Cer(d18:1/6:0) Urea; D-erythro-Urea-C6-Ceramide
Target:
Research Areas:
C6 Urea Ceramide (Cer(d18:1/6:0) Urea) is an inhibitor of neutral ceramidase. C6 Urea Ceramide increases total ceramide levels in wild-type mouse embryonic fibroblasts (MEFs) and HT-29 colon cancer cells. C6 Urea Ceramide (5-10 μM) inhibits proliferation of HT-29 cells and induces apoptosis and autophagy, but is not toxic to non-cancerous cells. C6 Urea Ceramide decreases total and phosphorylated β-catenin levels in HT-29 and HCT116 cells, and induces colocalization of β-catenin with the 20S proteasome. C6 Urea Ceramide (1.25, 2.5, and 5 mg/kg) reduced tumor growth and increased C16, C18, C20, and C24 ceramide levels in tumor tissues in the HT-29 mouse xenograft model.
Cat. No.: HY-P11250
Target:
Bacterial NO Synthase Interleukin Related Reactive Oxygen Species (ROS) Toll-like Receptor (TLR) ERK JNK p38 MAPK
Research Areas:
Cat. No.: HY-142975
CAS No.: 112726-51-9
Synonyms: C15 Galactosylceramide (d18:1/15:0); GalCer(d18:1/15:0)
N-Pentadecanoyl-psychosine is a glycolipid that can be used in membrane adhesion studies .
Cat. No.: HY-172666F
Synonyms: Biotin ceramide (d18:0/6:0)
Target:
Research Areas:
C6 Biotin dihydro ceramide is an affinity probe that allows C6 dihydro ceramide to be detected or immobilized through interaction with the biotin ligand.
Cat. No.: HY-139286
CAS No.: 1823021-14-2
Synonyms: Pacsph; Pacsphingosine (d18:1)
Target:
Research Areas:
Photoclick sphingosine (Pacsph) is a photosensitizing and clickable sphingosine analog. Photoclick sphingosine is metabolized in cells into endogenous lipid metabolic pathways and can be visualized by its clickable alkyne group. Photoclick sphingosine can be used to study intracellular sphingolipid metabolism and subcellular localization .
Cat. No.: HY-131676
CAS No.: 121999-64-2
Synonyms: SM (d18:1/17:0); Heptadecanoyl Sphingomyelin; N-Heptadecanoyl-D-erythro-Sphingosylphosphorylcholine
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Research Areas:
C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.
Cat. No.: HY-146904S
CAS No.: 2770684-34-7
Target:
Research Areas:
(S)-Keto sphinganine-d7 (hydrochloride) is deuterium labeled 3-Keto sphinganine.
Cat. No.: HY-171936
CAS No.: 1329115-44-7
Synonyms: GM1 (d18:1/C18:0) ammonium; C18 Ganglioside GM1 (d18:1/18:0) ammonium
Target:
Research Areas:
Ganglioside GM1 (ammonium) is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue. Ganglioside GM1 (ammonium) is one of the most abundant gangliosides in the brain which provides neuroprotection. Ganglioside GM1 (ammonium) exhibits anti-inflammatory property. Ganglioside GM1 (ammonium) has a well-balanced amphiphilic behavior. Ganglioside GM1 (ammonium) can reduce the fluidity of the plasma membrane that implies a retention and enrichment of the ganglioside in specific membrane domains that are called lipid rafts. Ganglioside GM1 (ammonium) can modify the process of differentiation, amplifies responses to neurotrophic factors, protects against excitatory amino acid-related neurotoxicity. Ganglioside GM1 (ammonium) can alleviate acute nerve cell damage through blocking cytotoxicity and potentiating neurotophic factors. Ganglioside GM1 (ammonium) can be studied in neurodegenerative diseases such as Alzheimer’s disease .
Cat. No.: HY-W019838R
CAS No.: 764-22-7
Synonyms: Sphinganine (d18:0) (Standard)
Category:
Cat. No.: HY-N15860
CAS No.: 112791-53-4
Category:
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
