2723 Results for "

THR

" in MedChemExpress (MCE) Product Catalog:
Products (2723)

2723 Results for "THR" in MCE Product Catalog:

Cat. No.: HY-P5632
Target:  

Bacterial

Research Areas:  

Infection

Bovine tracheal antimicrobial peptide is a kind of comes from the tracheal mucosa of antimicrobial peptides. Bovine tracheal antimicrobial peptide has activity against E.coli D31, K.pneumoniae 13883, S.aureus 25923, P.aeruginosa 27853 and C.albicans 14053, MIC value 12-25, 12-25, 25-50, 25-50, 6-12 μg/ml, respectively .
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Cat. No.: HY-P5800
Synonyms: μ-TrTx-Phlo1b
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Phlo1b (μ-TrTx-Phlo1b) is a peptide toxin contains 35-amino acid residues. Phlo1b is a selective Nav1.7 inhibitor. Phlo1b has a weak inhibitory effect on Nav1.2 and Nav1.5 .
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Cat. No.: HY-P5801
Synonyms: μ-TrTx-Phlo1a
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Phlo1a (μ-TrTx-Phlo1a) is a peptide toxin contains 35-amino acid residues. Phlo1b is a selective Nav1.7 inhibitor. Phlo1a has a weak inhibitory effect on Nav1.2 and Nav1.5 .
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Cat. No.: HY-P5868
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

mHuwentoxin-IV is a naturally modified Huwentoxin-IV (HY-P1220). mHuwentoxin-IV inhibits tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels of dorsal root ganglion neurons with an IC50 of 54.16 nM. mHuwentoxin-IV inhibition of tetrodotoxin-sensitive sodium channels is not reversed by strong depolarization voltages .
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Cat. No.: HY-P5900
Synonyms: m3-HwTx-IV
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

m3-Huwentoxin IV (m3-HwTx-IV) is a potent NaV inhibitor with IC50s of 3.3, 6.8, 7.2, 8.4, 11.9 and 369 nM against hNaV1.7, hNaV1.6, hNaV1.3, hNaV1.1, hNaV1.2 and hNaV1.4, respectively in QPatch assay. m3-Huwentoxin IV dose-dependently suppresses spontaneous pain induced by the NaV1.7 activator OD1 in a rodent pain model .
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Cat. No.: HY-P0089
CAS No.: 83930-13-6
Synonyms: Growth Hormone Releasing Factor human; Somatorelin (1-44) amide (human)
Target:  

GHR

Research Areas:  

Endocrinology

Human growth hormone-releasing factor (Growth Hormone Releasing Factor human) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary .
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Cat. No.: HY-P0089A
Synonyms: Growth Hormone Releasing Factor human TFA; Somatorelin (1-44) amide (human) TFA
Target:  

GHR

Research Areas:  

Endocrinology

Human growth hormone-releasing factor TFA (Growth Hormone Releasing Factor human TFA) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary .
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Cat. No.: HY-P1078
CAS No.: 1600543-88-1
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

Huwentoxin XVI, an analgesic, is a highly reversible and selective mammalian N-type calcium channel (IC50 of ~60 nM) antagonist from Chinese tarantula Ornithoctonus huwena. Huwentoxin XVI has no effect on voltagegated T-type calcium channels, potassium channels or sodium channels .
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Cat. No.: HY-P1078A
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

Huwentoxin XVI TFA, an analgesic, is a highly reversible and selective mammalian N-type calcium channel (IC50 of ~60 nM) antagonist from Chinese tarantula Ornithoctonus huwena. Huwentoxin XVI TFA has no effect on voltagegated T-type calcium channels, potassium channels or sodium channels .
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Cat. No.: HY-P1219
CAS No.: 925463-91-8
Synonyms: β-TRTX-Cj1α
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Jingzhaotoxin-III is a potent and selective blocker of Nav1.5 channels, with an IC50 of 348 nM, and shows no effect on other sodium channel isoforms. Jingzhaotoxin-III can selectively inhibit the activation of cardiac sodium channel but not neuronal subtypes, and hopefully represents an important ligand for discriminating cardiac VGSC subtype .
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Cat. No.: HY-P1281
CAS No.: 145199-73-1
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Kaliotoxin is a peptidyl inhibitor of neuronal BK-Type. Kaliotoxin can specific inhibit Kv channels and calcium-activated potassium channels. Kaliotoxin can be used for the research of the regulation of membrane potential and neuron excitability .
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Cat. No.: HY-P2538
CAS No.: 120796-97-6
Target:  

Vasopressin Receptor

Research Areas:  

Cardiovascular Disease

Big Endothelin-1 (1-38), human is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide .
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Cat. No.: HY-P2539
CAS No.: 120796-99-8
Target:  

Vasopressin Receptor

Research Areas:  

Cardiovascular Disease

Big Endothelin-1 (1-39), porcine is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide. Big Endothelin-1 (1-39), porcine has similar pressor effects in vivo .
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Cat. No.: HY-P4912
CAS No.: 2243219-82-9
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Big Endothelin-1 (rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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Cat. No.: HY-P5130
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

Big endothelin-1 (rat 1-39) is a 39-residues peptide. Big endothelin-1 (rat 1-39) induces diuretic and natriuretic response in conscious Sprague-Dawley rats. Big endothelin-1 (rat 1-39) raises blood pressure in mice .
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Cat. No.: HY-P5854
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Aa1 toxin, a neurotoxic peptide that can be obtained from the venom of Androctonus australis Garzoni, is a specific potassium channel blocker. Aa1 toxin can be used in the study of neurological diseases .
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Cat. No.: HY-P5931
CAS No.: 752984-66-0
Synonyms: Potassium channel toxin alpha-KTx 6.13; SPX; α-KTx6.13
Target:  

Potassium Channel

Research Areas:  

Inflammation/Immunology Cancer

Spinoxin isolated from the venom of scorpion Heterometrus spinifer, is a 34-residue peptide neurotoxin cross-linked by four disulfide bridges. Spinoxin is a potent inhibitor of Kv1.3 potassium channel (IC50 = 63 nM), considering to be valid molecular targets in the diagnostics and therapy of various autoimmune disorders and cancers .
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Cat. No.: HY-P10078
CAS No.: 90880-43-6
Research Areas:  

Endocrinology

pTH (39-84) (human) is the C-terminal fragment of parathyroid hormone (PTH). pTH (39-84) (human) increases Apoptosis. pTH (39-84) (human) can stimulate osteoclast formation .
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Cat. No.: HY-P10230
CAS No.: 207410-26-2
Target:  

Bacterial

Research Areas:  

Infection

Sublancin is an antimicrobial peptide, which inhibits DNA replication, transcription and translation, without affecting membrane integrity. Sublancin suppresses glucose uptake for the competition of phosphotransferase system (PTS). Sublancin inhibits B. subtilis strain 168 ΔSPβ with MIC of 0.312 μM .
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Cat. No.: HY-P10801
Synonyms: C46 peptide
Target:  

HIV

Research Areas:  

Infection

mC46 (C46) peptide is a membrane-associated fusion peptide inhibitor. mC46 peptide potently inhibits HIV-1 replication and entry. mC46 also inhibits CCR5-tropic, CXCR4-tropic, and dual-tropic HIVs, SIV, and SHIV .
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