2946 Results for "

TYR

" in MedChemExpress (MCE) Product Catalog:

Products (2946)

Sort by :

Categories

By Targets

Species:

Tags:

Sources:

Hosts:

Reactivities:

Applications:

Isotypes:

Conjugations:

Clonalities:

Modifications:

Products

Anthopleurin-A TFA

Cat. No.: HY-P4898A

Target:

Sodium Channel

Research Areas:

Cardiovascular Disease

Anthopleurin-A TFA is a soidum channel toxin. Anthopleurin-A TFA is selective for cardiac channels and has cardiotonic effect. Anthopleurin-A TFA can be isolated from the sea anemone .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Intermedin1-53 (Human)

Cat. No.: HY-P11289

Target:

Apoptosis

Research Areas:

Cardiovascular Disease

Intermedin1-53 (Human) is a 53-aa human calcitonin family peptide that reduces the vulnerability of atherosclerotic plaques by inhibiting CHOP-mediated macrophage apoptosis and inflammasome .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

SK56

Cat. No.: HY-P11603

Target:

Pyroptosis

Research Areas:

Inflammation/Immunology

SK56 is a GSDMD-NT pore inhibitor. SK56 inhibits pyroptosis (Pyroptosis) and the release of pyroptosis-related cytokines in macrophages and human peripheral blood leukocytes. SK56 prevents extensive cell death in human alveolar organoids in an organoid-macrophage co-culture model. SK56 prevents death from infectious shock induced by LPS (HY-D1056) or cecal ligation and puncture in mice. SK56 can be used in studies related to sepsis .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

GIPR/GLP-1R/GCGR agonist-1

Cat. No.: HY-P11818

Target:

GLP Receptor GCGR

Research Areas:

Metabolic Disease Inflammation/Immunology

GIPR/GLP-1R/GCGR agonist-1 (compound 686) is a triple receptor agonist with activity at GLP-1R, GIPR, and GCGR. GIPR/GLP-1R/GCGR agonist-1 functionally modulates target receptors to drive cAMP generation. GIPR/GLP-1R/GCGR agonist-1 can be used for the research of type 2 diabetes mellitus, obesity, nonalcoholic fatty liver disease .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

C-Type Natriuretic Peptide (1-53), human

Cat. No.: HY-P1815

CAS No.: 141294-77-1

Target:

Angiotensin Receptor

Research Areas:

Cardiovascular Disease Endocrinology

C-Type Natriuretic Peptide (1-53), human is the 1-53 fragment of C-Type Natriuretic Peptide. C-Type Natriuretic Peptide is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance and vascular tone .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

C-Type Natriuretic Peptide (1-53), human TFA

Cat. No.: HY-P1815A

Target:

Angiotensin Receptor

Research Areas:

Cardiovascular Disease Endocrinology

C-Type Natriuretic Peptide (1-53), human TFA is the 1-53 fragment of C-Type Natriuretic Peptide. C-Type Natriuretic Peptide TFA is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance and vascular tone .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Pezadeftide

Cat. No.: HY-P3384

CAS No.: 1907724-92-8

Target:

Fungal

Research Areas:

Others Inflammation/Immunology

Pezadeftide is a potent antifungal peptide. Pezadeftide can enter fungal cells and cause a rapid mitochondrial response that results in hyperpolarization of the mitochondrial membrane .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Noraramtide

Cat. No.: HY-P10563

CAS No.: 2580150-96-3

Synonyms: BHV-1100

Target:

CD38 IFNAR

Research Areas:

Cancer

Noraramtide (BHV-1100) is an antibody-recruiting molecule. Noraramtide binds to CD38 and recruits natural killer (NK) cells to mediate antibody-dependent cellular cytotoxicity. Noraramtide enhances the capacity of autologous cytokine-induced memory-like (CIML) NK cells to produce IFNγ and CD107a, thereby improving their cytotoxicity against multiple myeloma cells. Noraramtide can be used in the research of multiple myeloma .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

TLQP-62 (mouse,rat)

Cat. No.: HY-P11092

Target:

Endogenous Metabolite

Research Areas:

Neurological Disease

TLQP-62 (mouse,rat) is a secreted C-terminal peptide that can be derived from protein VGF. TLQP-62 activates the BDNF-TrkB signaling pathway, inducing acute, transient phosphorylation of TrkB receptor and downstream CREB (Ser133) phosphorylation. TLQP-62 demonstrates excellent efficacy in promoting long-term fear memory formationin wild-type mice and reversing memory impairment in VGF heterozygous knock-out mice. TLQP-62 can be used for the study of memory-related neurological disorders (e.g., Alzheimer’s disease, frontotemporal dementia) .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Tau Peptide (255-314) (Repeat 2 Domain) (human)

Cat. No.: HY-P4933

CAS No.: 2022995-68-0

Synonyms: Tau-F protein (255-314)

Target:

Tau Protein

Research Areas:

Neurological Disease

Tau Peptide (255-314) (Repeat 2 Domain) (human) (Tau-F protein (255-314)) is a polypeptide. Tau Peptide (255-314) (human) is the 255-314 fragment of Tau-F (also known as Tau-4, the 2N4 isoform), a major isoform of the Tau protein. Tau Peptide (255-314) (human) contains two core driving sequences for Tau aggregation, namely PHF6* (275-280, VQIINK) and PHF6 (306-311, VQIVYK), and spans the C-terminal half of repeat domain R1, the entire repeat domain R2, and the N-terminal half of repeat domain R3 within the microtubule-binding region (MTBR).

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Mambalgin-2

Cat. No.: HY-P5863

Synonyms: Mamb-2

Target:

Sodium Channel

Research Areas:

Neurological Disease

Mambalgin-2 (Mamb-2) is an acid-sensitive ion channels (ASICs) inhibitor and a venom peptide. Mambalgin-2 can be obtained from the venom of the African black mamba. Mambalgin-2 can be used in the study of pain and neurological diseases .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Ecallantide

Cat. No.: HY-108814

CAS No.: 460738-38-9

Synonyms: DX-88

Target:

Kallikrein

Research Areas:

Cardiovascular Disease

Ecallantide (DX-88) is a specific plasma kallikrein inhibitor. Ecallantide inhibits the production of bradykinin. Ecallantide can be used to prevent acute attacks of angioedema .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Relaxin H3 (human)

Cat. No.: HY-P4890

CAS No.: 1158181-62-4

Target:

RXFP Receptor Reactive Oxygen Species (ROS) Pyroptosis Caspase Interleukin Related TGF-beta/Smad AMPK Apoptosis

Research Areas:

Metabolic Disease Inflammation/Immunology

Relaxin H3 (human) is a relaxin peptide with anti-inflammatory, anti-apoptotic, anti-pyroptotic, anti-migratory, protective and anti-fibrotic activities. Relaxin H3 (human) acts on RXFP1 to generate cAMP and reduce the levels of ATP and ROS. Relaxin H3 (human) inhibits renal inflammatory pyroptosis (pyroptosis), NLRP3 inflammasome activation, caspase-1 activation, IL-1β/IL-18 secretion, collagen synthesis, TGF-β1 signaling pathway, Smad2 phosphorylation, myofibroblast differentiation, TIMP expression, and HRMEC migration. Relaxin H3 (human) activates AMPK, upregulates MFN2 expression, improves mitochondrial quality control and membrane potential, inhibits apoptosis (apoptosis) and pyroptosis, restores retinal ultrastructure, and reverses excessive left ventricular collagen expression. Relaxin H3 (human) can be used in studies related to kidney stones, nephrocalcinosis, diabetic cardiomyopathy, fibrotic cardiomyopathy, and diabetic retinopathy .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Relaxin H3 (human) TFA

Cat. No.: HY-P4890A

Target:

RXFP Receptor Reactive Oxygen Species (ROS) Pyroptosis Caspase Interleukin Related TGF-beta/Smad AMPK Apoptosis

Research Areas:

Metabolic Disease Inflammation/Immunology

Relaxin H3 (human) TFA is a relaxin peptide with anti-inflammatory, anti-apoptotic, anti-pyroptotic, anti-migratory, protective and anti-fibrotic activities. Relaxin H3 (human) TFA acts on RXFP1 to generate cAMP and reduce the levels of ATP and ROS. Relaxin H3 (human) TFA inhibits renal inflammatory pyroptosis (pyroptosis), NLRP3 inflammasome activation, caspase-1 activation, IL-1β/IL-18 secretion, collagen synthesis, TGF-β1 signaling pathway, Smad2 phosphorylation, myofibroblast differentiation, TIMP expression, and HRMEC migration. Relaxin H3 (human) TFA activates AMPK, upregulates MFN2 expression, improves mitochondrial quality control and membrane potential, inhibits apoptosis (apoptosis) and pyroptosis, restores retinal ultrastructure, and reverses excessive left ventricular collagen expression. Relaxin H3 (human) TFA can be used in studies related to kidney stones, nephrocalcinosis, diabetic cardiomyopathy, fibrotic cardiomyopathy, and diabetic retinopathy .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Latartoxin-1a

Cat. No.: HY-P5176

Synonyms: LtTx-1a

Target:

Inhibitory Antibodies

Research Areas:

Neurological Disease

Latartoxin-1a (LtTx-1a) is a peptide toxin can be isolated from L. tarabaevi. Latartoxin-1a is paralytic and lethal to insects and has membrane-bound activity .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Zenagamtide

Cat. No.: HY-P11274

CAS No.: 3005889-81-3

Synonyms: Amycretin; NN 9487

Target:

Amylin Receptor GCGR Insulin Receptor

Research Areas:

Metabolic Disease

Zenagamtide (Amycretin; NN 9487) is an orally active, blood-brain barrier permeable triple agonist that targets GLP-1, amylin (Amylin Receptor) and calcitonin receptor (Calcitonin Receptor). Zenagamtide is a single peptide consisting of 68 amino acids that can target brain regions regulating food intake, significantly suppress appetite and reduce energy intake. Therefore, Zenagamtide improves body weight, waist circumference, glycated hemoglobin and lipid profile, and also alleviates the histological features of metabolic dysfunction-associated steatotic liver disease (MASLD) and enhances insulin sensitivity. Zenagamtide may cause transient increases in heart rate and fluctuations in serum calcium levels, but it is an important compound for the study of overweight, obesity, insulin resistance and related metabolic diseases .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Zenagamtide sodium

Cat. No.: HY-P11274A

Synonyms: Amycretin sodium; NN 9487 sodium

Target:

Amylin Receptor Insulin Receptor GCGR

Research Areas:

Metabolic Disease

Zenagamtide (Amycretin; NN 9487) sodium is an orally active, blood-brain barrier permeable triple agonist that targets GLP-1, amylin (Amylin Receptor) and calcitonin receptor (Calcitonin Receptor). Zenagamtide sodium is a single peptide consisting of 68 amino acids that can target brain regions regulating food intake, significantly suppress appetite and reduce energy intake. Therefore, Zenagamtide sodium improves body weight, waist circumference, glycated hemoglobin and lipid profile, and also alleviates the histological features of metabolic dysfunction-associated steatotic liver disease (MASLD) and enhances insulin sensitivity. Zenagamtide sodium may cause transient increases in heart rate and fluctuations in serum calcium levels, but it is an important compound for the study of overweight, obesity, insulin resistance and related metabolic diseases .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Lytx-Pa2a

Cat. No.: HY-P11442

Synonyms: Lycotoxin-Pa2a; TBIU041425

Target:

Bacterial Toll-like Receptor (TLR)

Research Areas:

Inflammation/Immunology

Lytx-Pa2a (Lycotoxin-Pa2a) is a peptide inhibitor against bacterial membranes and TLR4 receptor. Lytx-Pa2a exerts antimicrobial effects via non-competitive disruption of outer/cytoplasmic membranes and suppression of LPS-induced TLR4/NF-κB signaling. Lytx-Pa2a is promising for research of bacterial infection and inflammation-related disease (e.g., sepsis) .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

MmTx2 toxin

Cat. No.: HY-P5857

Synonyms: Micrurotoxin 2

Target:

GABA Receptor

Research Areas:

Neurological Disease

MmTx2 toxin is a GABA_A receptor modulator that enhances GABA_A receptor sensitivity to agonists. MmTx2 toxin can be obtained from venom of coral snake. MmTx2 toxin can be used in the study of neurological diseases such as epilepsy, schizophrenia and chronic pain .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

MmTx1 toxin

Cat. No.: HY-P5860

Synonyms: Micrurotoxin 1

Target:

GABA Receptor

Research Areas:

Neurological Disease

MmTx1 toxin (Micrurotoxin 1) is an allosteric GABA_A receptor modulator that increases GABA_A receptor susceptibility to agonist .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Type


Products	/ In-stock - + Please select quantity Expand Add to Cart
Cat. No.
Purity
Feature
CAS No.
Storage
Solvent & Solubility
Appearance
Formulation
Species
Source
Tag
Endotoxin Level
Biological Activity
Storage & Stability
Shipping
Host
Reactivity
Dilution Ratio
Conjugation
Clonality
Immunogen
SwissProt ID
Initial Source
Emission (Em)
Excitation (Ex)
Sequence Shortening
Isotype
Gene ID
Accession
Application
Reconsititution
Molecular Weight
Enzyme Activity
Specific Activity
In Vitro
In Vivo
Size	/ In-stock - + Add to Cart Bulk Inquiry Please select quantity

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity: