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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
MSCs
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "MSCs" in MCE Product Catalog:
Cat. No.: HY-101611R
CAS No.: 1883423-59-3
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MSC2530818 (Standard) is the analytical standard of MSC2530818. This product is intended for research and analytical applications. MSC2530818 is a potent, selective and orally available CDK8 inhibitor with an IC50 of 2.6 nM for CDK8.
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SJA710-6 is a small molecule able to selectively differentiate MSCs toward hepatocyte-like cells .
Cat. No.: HY-160053
Gint4.T aptamer sodium is a nuclease-resistant RNA aptamer-based antagonist targeting platelet-derived growth factor receptor beta (PDGFRβ) (Kd: 9.6 nM). Gint4.T aptamer sodium inhibits PDGFRβ heterodimerization and EGFR transactivation. It can significantly inhibit cell migration and proliferation, induce differentiation and prevent tumor growth in vivo. Gint4.T aptamer sodium specifically inhibits PDGFRβ-mediated tropism of mesenchymal stem cells (MSCs) toward the tumor microenvironment .
Cat. No.: HY-177058
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DSP30 is a phosphorothioate cpG-oligodeoxynucleotide and a TLR9 agonist. DSP30 can activate immune system cells, including B cells and dendritic cells, by inducing proliferation and cytokine production.DSP30 can enhance the immunosuppressive function of bone marrow-multipotent mesenchymal stromal cells (BM-MSC). DSP30 combined with interleukin 2 (IL2) is an effective mitotic stimulant in B-cell disorders. DSP30 can be used for the genetic characteristic research and analysis of chronic lymphocytic leukemia (CLL) .
Cat. No.: HY-185057
CAS No.: 41656-56-8
Synonyms: S-Lactylglutathione; (R)-S-Lactoylglutathione
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Cat. No.: HY-P11346
CAS No.: 1830290-52-2
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Cat. No.: HY-108438
CAS No.: 1201916-31-5
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TCS 2210 (compound 1) is a neuronal differentiation inducer in mesenchymal stem cells (MSCs). TCS 2210 increases expression of the neuronal markers β-III tubulin and neuron-specific enolase (NSE) .
Cat. No.: HY-N0898AR
CAS No.: 18829-70-4
Synonyms: (-)-Cianidanol (Standard); (-)-Catechuic acid (Standard)
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Cat. No.: HY-RS08707
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MSC Human Pre-designed siRNA Set A contains three designed siRNAs for MSC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23460
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Msc Rat Pre-designed siRNA Set A contains three designed siRNAs for Msc gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-110262
CAS No.: 1124381-43-6
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MSC 2032964A is an orally active, selective inhibitor for apoptosis signal-regulating kinase 1(ASK1) with IC50 of 96 nM. MSC 2032964A preserves the visual responses in EAE mice model and exhibits potency in ameliorating the neuroinflammation .
Cat. No.: HY-153332
CAS No.: 1460285-69-1
Tankyrase-IN-5 (Compound 30f), an analogue of MSC2504877 (HY-123851), is a tankyrase TNKS1 and TNKS2 inhibitor with IC50s of 2.3 nM and 7.9 nM, respectively .
Cat. No.: HY-N8917
CAS No.: 1180504-64-6
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Cat. No.: HY-P3413
CAS No.: 683750-83-6
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Cat. No.: HY-147511
CAS No.: 2569295-93-6
PPARγ agonist 7 (Compound 3a) is a potent and selective agonist of PPARγ. PPARγ agonist 7 promotes adiponectin production in human bone marrow mesenchymal stem cells (hBM-MSCs) as a novel PPARγ full agonist (EC50, 4.34 μM) .
Cat. No.: HY-N0008R
CAS No.: 21082-33-7
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Cat. No.: HY-P0306A
Synonyms: Heparin Binding Peptide TFA
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Cat. No.: HY-170581
CAS No.: 3116771-70-8
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PPARγ/δ modulator 2 (Compound 3h) is a PPARγ agonist and PPARδ antagonist. The Ki values for PPARγ and PPARδ are 2.8 μM and 43 nM, respectively. PPARγ/δ modulator 2 significantly enhances the production of Adiponectin and promotes adipogenic differentiation of human bone marrow mesenchymal stem cells (hBM-MSCs). PPARγ/δ modulator 2 can be used in the study of metabolic disorders associated with hypoadiponectinemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
