35 Results for "

NADPH-dependent 3

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "NADPH-dependent 3" in MCE Product Catalog:

Cat. No.: HY-P80590A
Synonyms: 15 hydroxyprostaglandin dehydrogenase [NADP ]; 15-hydroxyprostaglandin dehydrogenase [NADP ]; Carbonyl reductase [NADPH] 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1; Prostaglandin 9 ketoreduc

Host:  

Mouse

Application:  

WB, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-E71774
Research Areas:  

Others

3-Oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) is an NADPH-dependent β-ketoacyl-ACP reductase and a key enzyme in the bacterial type II fatty acid synthesis pathway.
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Cat. No.: HY-P76172
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BLVRB; Green Heme-Binding Protein; Prev. FLR; GHBP; S-Nitroso-CoA-Assisted Nitrosyltransferase; FR; Biliverdin-IX Beta-Reductase; Biliverdin Reductase B (Flavin Reductase (NADPH)); NADPH-dependent Diaphorase; Epididymis Secretory Protein Li 10; Flavin Red
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-187119
CAS No.: 158575-73-6
Target:  

Aldose Reductase

Research Areas:  

Metabolic Disease

CC13401 is an aldose reductase (ALR2) inhibitor with an IC50 of 41.41 μM in rats. CC13401 inhibits the NADPH-dependent reduction reaction catalyzed by ALR2. CC13401 can be used in studies on the mechanisms related to the polyol pathway and diabetic complications .
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Cat. No.: HY-P85567
Synonyms: 15 hydroxyprostaglandin dehydrogenase [NADP ]; 15-hydroxyprostaglandin dehydrogenase [NADP ]; Carbonyl reductase [NADPH] 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1; Prostaglandin 9 ketoreductase; Prostaglandin 9-ketoreductase; Prostaglandin E; 2; 9 reductase; Prostaglandin-E; 2; 9-reductase; SDR21C1.

Host:  

Mouse

Application:  

WB, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-E71567
Research Areas:  

Others

2-Hydroxymethylglutarate dehydrogenase (EC 1.1.1.291) is an NADPH-dependent D-ribulose reductase—a type of oxidoreductase—that catalyzes the reduction of D-ribulose to D-arabitol. It plays a key role in pentose metabolism, sugar alcohol metabolism, and carbon source utilization in microorganisms and fungi.
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Cat. No.: HY-E71653
Research Areas:  

Others

3,9-Dihydroxypterocarpan 6a-monooxygenase (EC 1.14.13.28) is a plant cytochrome P450 monooxygenase that hydroxylates 3,9-dihydroxypterocarpan via an NADPH-dependent oxidation reaction, participating in the biosynthesis of glyceollin—a disease-resistance metabolite found in legumes such as soybean.
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Cat. No.: HY-187733
CAS No.: 77016-85-4
Research Areas:  

Cancer

Plomestane is an orally active second-generation steroidal aromatase inhibitor that, as an enzyme-activated pseudosubstrate, is converted via NADPH-dependent catalysis into a reactive intermediate, which covalently binds to aromatase to produce irreversible inhibition, thereby persistently suppressing peripheral aromatase activity. Plomestane can be used for the study of hormone-dependent breast cancer .
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Cat. No.: HY-P704102
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: VAT1L; Vesicle Amine Transport 1 Like; KIAA1576; Vesicle Amine Transport Protein 1 Homolog (T. California)-Like; Putative NADPH-dependent Quinone Oxidoreductase VAT1L; Synaptic Vesicle Membrane Protein VAT-1 Homolog-Like; Vesicle Amine Transport Protein 1
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-E71772A
Research Areas:  

Others

3-Oxo-5-β-steroid 4-dehydrogenase from human (Recombinant) (EC 1.3.1.3) belongs to the NADPH-dependent short-chain dehydrogenase/reductase superfamily (AKR family). It catalyzes the 5β-reduction of the Δ4 double bond in steroid molecules and is involved in bile acid synthesis and steroid hormone metabolism, serving as a crucial enzyme for maintaining hepatic cholesterol metabolism and endocrine homeostasis.
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Cat. No.: HY-P72272
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CBR1; Carbonyl Reductase [NADPH] 1; Prev. CBR; Short Chain Dehydrogenase/Reductase Family 21C, Member 1; SDR21C1; 15-Hydroxyprostaglandin Dehydrogenase [NADP(+)]; Short Chain Dehydrogenase/Reductase Family 21C Member 1; Epididymis Secretory Sperm Binding Protein; 20-Beta-Hydroxysteroid Dehydrogenase; 15-Hydroxyprostaglandin Dehydrogenase; NADPH-dependent Carbonyl Reductase 1; Carbonyl Reductase (NADPH) 1; Alcohol Dehydrogenase [NAD(P)+] CBR1; Carbonyl Reductase (NADPH); Prostaglandin-E(2) 9-Reductase; HCBR1; Prostaglandin 9-Ketoreductase; CRN; Carbonyl Reductase 1; PG-9-KR
Species:  
Human
Source:  
P. pastoris
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Cat. No.: HY-122940R
CAS No.: 644-06-4
Synonyms: Ageratochromene (Standard)
Precocene II (Standard) is the analytical standard of Precocene II (HY-122940). This product is intended for research and analytical applications. Precocene II (Ageratochromene) is a plant larva hormone antagonists that inhibits the biosynthesis of juvenile hormone. Precocene II inhibits corpora allata function and downregulates juvenile hormone levels, while exerting multiple effects including inducing precocious metamorphosis, forming macropterous morphs, inhibiting ovarian growth, producing cytotoxicity, disrupting insect development, and causing sterility and kidney damage. Precocene II blocks normal nymphal development, causes renal tubular damage and increases blood urea nitrogen levels, and also blocks juvenile hormone biosynthesis in vitro. Precocene II undergoes oxidative metabolism catalyzed by NADPH-dependent monooxygenase to generate a variety of metabolites. Precocene II can be applied in studies related to insect growth regulation and nephrotoxicity [3] .
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Cat. No.: HY-187975
CAS No.: 917613-59-3
Research Areas:  

Cardiovascular Disease

MT-1207 free base is an orally active, selective adrenergic α1 and 5-HT2A receptor antagonist. MT-1207 has IC50 values of <0.1 nM, 0.15 nM, 1.40 nM, and 0.27 nM for α1A, α1B, α1D, and 5-HT2A, respectively. MT-1207 free base induces vasodilation, improves baroreflex sensitivity, and reduces heart rate in isolated hearts. MT-1207 free base lowers blood pressure, protects the heart, brain, and kidneys, improves cognition, delays stroke, reduces mortality, and lowers uric acid without impairing renal function in SHR/2K1C/2K2C models. MT-1207 free base exhibits high plasma protein binding, resistance to plasma esterases, and NADPH-dependent hepatic metabolism. MT-1207 free base can be used for research related to hypertension [3].
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Cat. No.: HY-184860
CAS No.: 3913-64-2
Synonyms: (2S)-Hydroxypropanal
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

L-Lactaldehyde ((2S)-Hydroxypropanal) is a chiral aldehyde, metabolic intermediate, and enzyme substrate. L-Lactaldehyde is oxidized to L-lactate by NAD-dependent lactaldehyde dehydrogenase. L-Lactaldehyde is reduced to L-1,2-propanediol by NADH/NADPH-dependent oxidoreductases. L-Lactaldehyde is used in studies of microbial sugar metabolism and carbonyl metabolism [3].
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Cat. No.: HY-P701217
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PTGR1; ZADH3; Prev. LTB4DH; D3T-Inducible Gene 1 Protein; Leukotriene B4 12-Hydroxydehydrogenase; DIG-1; NAD(P)H-dependent Alkenal/One Oxidoreductase; PRG-1; Dithiolethione-Inducible Gene 1 Protein; NADP-dependent Leukotriene B4 12-Hydroxydehydrogenase; 1
Species:  
Human
Source:  
HEK293
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