55 Results for "

SOCs

" in MedChemExpress (MCE) Product Catalog:
Products (55)

55 Results for "SOCs" in MCE Product Catalog:

Cat. No.: HY-126420
CAS No.: 57685-46-8
Purity:  ≥99.0%
Kansuinine B is a natural diterpenoid compound with anti-inflammatory, anti-cancer and anti-viral activities, which can be isolated from the roots of Euphorbia kansui. Kansuinine B induces sustained ERK1/2 activation, inhibits IL-6-induced Stat3 activation and tyrosine phosphorylation, and enhances serine phosphorylation of Stat3. Kansuinine B negatively regulates the IL-6 signaling pathway by upregulating the expression of SOCS-3. Kansuinine B promotes the proliferation of mouse splenic lymphocytes in vitro and stimulates rat peritoneal macrophages to produce NO. Kansuinine B can be used in studies related to liver cancer and COVID-19 .
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Cat. No.: HY-13812R
CAS No.: 545380-34-5
Synonyms: EVP4593 (Standard)
QNZ (Standard) is the analytical standard of QNZ. This product is intended for research and analytical applications. QNZ (EVP4593) shows strong inhibitory effects on NF-κB transcriptional activation and TNF-α production with IC50s of 11 and 7 nM, respectively. QNZ (EVP4593) is a neuroprotective inhibitor of SOC channel.
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Cat. No.: HY-RS13552
Research Areas:  

Others

SOCS1 Human Pre-designed siRNA Set A contains three designed siRNAs for SOCS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS13554
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Others

SOCS3 Human Pre-designed siRNA Set A contains three designed siRNAs for SOCS3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS13555
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SOCS4 Human Pre-designed siRNA Set A contains three designed siRNAs for SOCS4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS13556
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SOCS5 Human Pre-designed siRNA Set A contains three designed siRNAs for SOCS5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS13557
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SOCS6 Human Pre-designed siRNA Set A contains three designed siRNAs for SOCS6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS13558
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SOCS7 Human Pre-designed siRNA Set A contains three designed siRNAs for SOCS7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS18546
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Socs2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Socs2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS25028
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Socs2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Socs2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS19885
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Cish Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cish gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P10385
CAS No.: 2244164-71-2
Target:  

NO Synthase

Research Areas:  

Infection

SPSB2-iNOS inhibitory cyclic peptide-3 (Compound CP3) is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 7 nM .
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Cat. No.: HY-P10384
CAS No.: 1989528-33-7
Target:  

NO Synthase

Research Areas:  

Infection

SPSB2-iNOS inhibitory cyclic peptide-2 (Compound CP2) is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 21 nM. SPSB2-iNOS inhibitory cyclic peptide-2 is reduction-resistant and oxidatively stable .
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Cat. No.: HY-117511
CAS No.: 1430420-02-2
Research Areas:  

Others

HJC0123 is a STAT3 inhibitor. HJC0123 inhibits the proliferation of hepatic stellate cells and induces cell cycle arrest and apoptosis. HJC0123 reduces the phosphorylation, nuclear translocation and transcriptional activities of STAT3, increases the production of IL-6, inhibits the phosphorylation of Smad2/3 and down-regulates SOCS3. HJC0123 can be used in the study of liver fibrosis .
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Cat. No.: HY-P10385A
Target:  

NO Synthase

Research Areas:  

Infection

SPSB2-iNOS inhibitory cyclic peptide-3 TFA is the TFA salt form of SPSB2-iNOS inhibitory cyclic peptide-3 (HY-P10385). SPSB2-iNOS inhibitory cyclic peptide-3 TFA is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 7 nM .
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Cat. No.: HY-P10384A
Target:  

NO Synthase

Research Areas:  

Infection

SPSB2-iNOS inhibitory cyclic peptide-2 TFA is the TFA salt form of SPSB2-iNOS inhibitory cyclic peptide-2 (HY-P10384). SPSB2-iNOS inhibitory cyclic peptide-2 TFA is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 21 nM. SPSB2-iNOS inhibitory cyclic peptide-2 TFA is reduction-resistant and oxidatively stable .
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Cat. No.: HY-P10383A
Target:  

NO Synthase

Research Areas:  

Infection

SPSB2-iNOS inhibitory cyclic peptide-1 TFA is the TFA salt form of SPSB2-iNOS inhibitory cyclic peptide-1(HY-P10383). SPSB2-iNOS inhibitory cyclic peptide-1 is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 4.4 nM. SPSB2-iNOS inhibitory cyclic peptide-1 is resistant to the proteases pepsin, trypsin and α-chymotrypsin. SPSB2-iNOS inhibitory cyclic peptide-1 is stable in human plasma and in oxidative environment .
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Cat. No.: HY-RS13553
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Others

SOCS2 Human Pre-designed siRNA Set A contains three designed siRNAs for SOCS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23359
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Others

Socs3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Socs3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24177
Research Areas:  

Others

Socs1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Socs1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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