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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
336 Results for "
St
" in MedChemExpress (MCE) Product Catalog:
Products (336)
336 Results for "St" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P74876
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HTRA2; Serine Protease 25; Prev. PRSS25; Protease, Serine, 25; OMI; Epididymis Secretory Sperm Binding Protein; High Temperature Requirement Protein A2; Mitochondrial Serine Protease; Serine Protease HTRA2, Mitochondrial; HtrA-Like Serine Protease; Omi St
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P700200AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL24; IL-4-Induced Secreted Protein; Prev. St16; Mob-5; Interleukin-24; MDA7; IL10B; Melanoma Differentiation Association Protein 7; IL-24; Suppression Of Tumorigenicity 16 Protein; C49A; Melanocyte-Associated Mda-7; FISP; MDA-7; Suppression Of Tumorigeni
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P76666
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SULT2B1; Sulfotransferase 2B1; Sulfotransferase Family 2B Member 1; St2B1; HSSt2; Sulfotransferase Family Cytosolic 2B Member 1; Sulfotransferase Family, Cytosolic, 2B, Member 1; HydroxySteroid Sulfotransferase SULT2B1a; HydroxySteroid Sulfotransferase 2
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P7262
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL20; Chemokine (C-C Motif) Ligand 20; Prev. SCYA20; C-C Motif Chemokine 20; LARC; CC Chemokine LARC; MIP-3a; MIP-3-Alpha; St38; Exodus-1; CKb4; MIP3A; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 20; Beta Chemokine Exodus-1; Liver And Activati
Species:
Human
Source:
E. coli
Cat. No.: HY-B0063
CAS No.: 292618-32-7
Synonyms: St1481
Target:
Research Areas:
Gimatecan (ST1481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity .
Synonyms: OGT-IN-2
Target:
Research Areas:
ST045849 (OGT-IN-2) is a small-molecule OGT inhibitor with an IC50 of 30 μM against sOGT and 53 μM against ncOGT. ST045849 is applicable to research on metabolism-related diseases .
Cat. No.: HY-173496
CAS No.: 192876-13-4
Target:
Research Areas:
ST6GAL1-IN-1 is an orally active selective ST6GAL1 inhibitor (IC50 = 20 μM). ST6GAL1-IN-1 exhibits high antimetastatic potential, effectively inhibiting the migration of MDA-MB-231 cells at noncytotoxic concentrations. ST6GAL1-IN-1 can disrupt integrin sialylation in MDA-MB-231 cells. ST6GAL1-IN-1 inhibits tumor angiogenesis and cancer metastasis via the Integrin/VEGFR2-mediated signaling pathway. ST6GAL1-IN-1 effectively suppresses both tumor growth and cancer metastasis on the MDA-MB-231 xenograft model. ST6GAL1-IN-1 can be used for the study of Triple-negative breast cancer (TNBC) .
Target:
Research Areas:
Desglymidodrine (ST 1059), the active metabolite of Midodrine(HY-12749), is a selective α1-adrenoceptor agonist. Desglymidodrine is an effective arterial and venous vasoconstrictor and can be used to regulate blood pressure .
Cat. No.: HY-168532
CAS No.: 3099811-61-4
Target:
Research Areas:
ST2-IN-1 is a ST2 inhibitor. ST2-IN-1 blocks the binding interaction between ST2 and IL-33, thereby attenuating the downstream ST2/IL-33 signaling pathway. ST2-IN-1 reduces IL-1β release from mast cells and alleviates ST2 upregulation in cells. ST2-IN-1 can be used for research on inflammatory and immune-related diseases .
Cat. No.: HY-P10904
CAS No.: 51486-77-2
Synonyms: St-100
Target:
Research Areas:
ST-148 maleate is a potent and orally active DENV inhibitor. ST-148 maleate shows antiviral efficacy and low cell toxicity. ST-148 alters the interaction between lipid droplets and the C protein, thereby inhibiting viral replication. .
ST1074 is a dual CerS2/CerS4 inhibitor that induces apoptosis. ST1074 can be used in cancer research .
Target:
Research Areas:
ST247 a potent PPARβ/δ inverse agonist. ST247 has a higher affinity to PPARβ/δ. ST247 modulates expression of the activation marker CCL2 in the opposite direction. ST247 efficiently induces the interaction with corepressors. ST247 inhibits the agonist-induced transcriptional activity of PPARβ/δ .
Target:
Research Areas:
ST91 is a α2-adrenoceptor (α2AR) agonist. ST91 activates both α2AAR and non-α2AAR subtypes to produce spinal antinociception .
Cat. No.: HY-105003
CAS No.: 496955-42-1
Target:
Research Areas:
ST 1535 is a potent and orally active A2A adenosine receptor antagonist. ST 1535 shows antiparkinsonian activity and antitremorigenic effects. ST 1535 has the potential for the research of Parkinson’s disease .
Cat. No.: HY-114383
CAS No.: 1040754-67-3
Target:
Research Areas:
ST-539 is the inhibitor for deubiquitinase USP30 with IC50 of 0.37 μM. ST-539 promotes the ubiquitination of mitochondrial proteins, and induces mitochondrial autophagy, thereby regulating mitochondrial homeostasis. ST-539 can be used in research of neurodegenerative diseases .
Cat. No.: HY-121663
CAS No.: 400863-77-6
Target:
Research Areas:
ST-148 is a novel small molecule compound that has potent inhibitory effects against all four dengue virus serotypes. In the nonlethal AG129 mouse dengue virus infection model, ST-148 significantly reduced viremia and viral load in vital organs and tended to reduce plasma cytokine levels. Compound resistance was associated with the dengue virus capsid (C) gene, and the direct interaction of ST-148 with the C protein was presumed to be achieved through the protein's built-in fluorescence change in the presence of the compound. Therefore, ST-148 appears to interact with the dengue virus C protein and inhibit one or more unique steps of the viral replication cycle.
Cat. No.: HY-P2624A
Target:
Research Areas:
Cat. No.: HY-175231
Target:
Research Areas:
ST171 is a bitopic 5-HT1AR agonist with an Ki of 0.41 nM. ST171 selectively activates Gi/o signaling pathway and inhibits 5-HT1AR-mediated cAMP accumulation without Gs activation and marginal β-arrestin recruitment. T171 reduces hypersensitivity in chronic neuropathic and inflammatory pain mice model. ST171 can be used for pain research .
Cat. No.: HY-15668
CAS No.: 1370037-59-4
Target:
Research Areas:
ST09 is an efficient and low toxicity Curcumin (HY-N0005) derivative. ST09 significantly inhibits cell migration and downregulates the expression of MMP1, MMP2, and Vimentin. ST09 has strong cytotoxicity to breast cancer cells, such as MDA-MB-231, MCF7 and T47D cells. ST09 induces cell apoptosis by upregulating Bax and cleaved caspase-3/9. ST09 can be used in the research of cancer such as breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
