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OGT-IN-2 

Cat. No.: HY-136282
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OGT-IN-2 is a O-GlcNAc transferase (OGT) inhibitor with an IC50 of 53 μM. OGT-IN-2 reduces proliferation and viability of prostate cancer cells in vitro. OGT-IN-2 depletes intracellular alanine and decreases glucose consumption by cancer cells. OGT-IN-2 decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice.

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OGT-IN-2 Chemical Structure

OGT-IN-2 Chemical Structure

CAS No. : 442665-87-4

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Description

OGT-IN-2 is a O-GlcNAc transferase (OGT) inhibitor with an IC50 of 53 μM. OGT-IN-2 reduces proliferation and viability of prostate cancer cells in vitro. OGT-IN-2 depletes intracellular alanine and decreases glucose consumption by cancer cells. OGT-IN-2 decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice.

Molecular Weight

446.99

Formula

C₂₃H₂₇ClN₂O₃S

CAS No.

442665-87-4

SMILES

O=C(C1)N(/C(SC1C(O)=O)=N/C(C=C2)=CC=C2Cl)CCC3(C[[email protected]](C4)C5)C[[email protected]]5C[[email protected]]4C3

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Keywords:

OGT-IN-2OthersInhibitorinhibitorinhibit

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