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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
134 Results for "
cellular oxidation
" in MedChemExpress (MCE) Product Catalog:
Products (134)
134 Results for "cellular oxidation" in MCE Product Catalog:
Cat. No.: HY-114293A
CAS No.: 75520-41-1
Synonyms: Acetyl-CoA trilithium
Cat. No.: HY-N0594
CAS No.: 14259-55-3
Category:
Iridoids Terpenoids Rubiaceae Plants Morinda officinalis How Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-W003969
CAS No.: 695-34-1
Synonyms: Ascensil; 2-Amino-4-methylpyridine
Target:
Research Areas:
Aminopicoline (Ascensil) is a potent and non-selective inhibitor of nitric oxide synthase (NOS) isoenzymes (iNOS, nNOS, eNOS). Aminopicoline competes with arginine at the substrate-binding site of nitric oxide synthase, reduces cellular nitric oxide production, inhibits the elevation of plasma nitrate, increases mean arterial pressure at high doses, and also serves as a basis for radiolabeled ligands to localize nitric oxide synthase binding sites. Aminopicoline can be used in the research of diseases associated with septic shock, joint inflammation, intestinal inflammation, and CNS inflammation .
Cat. No.: HY-16772
CAS No.: 1213269-98-7
Synonyms: α-Tocotrienol quinone; PTC-743; Vatiquinone; NCT04378075
Target:
Research Areas:
EPI-743 (Vatiquinone; α-Tocotrienol quinone; PTC-743; NCT04378075) is a potent cellular oxidative stress protectant, inhibits ferroptosis in cells, which could be used for the study for mitochondrial diseases. EPI-743 is a synthetic analog of vitamin E with oral activity, targets repletion of reduced intracellular glutathione .
Cat. No.: HY-N1967
CAS No.: 76474-56-1
Category:
Zingiber officinale Roscoe Metabolic Disease Phenols Polyphenols Plants Disease Research Fields Zingiberaceae
Target:
Cat. No.: HY-174216
CAS No.: 3068830-89-4
Research Areas:
PZL-A is a activator of mitochondrial DNA (mtDNA) synthesis. PZL-A restores wild-type-like activity to mutant forms of polymerase γ (POLγ) with AC50 s of 160 and 20 nM for A467T and G848S. PZL-A activates mtDNA synthesis in cells, enhancing biogenesis of the oxidative phosphorylation machinery and cellular respiration. PZL-A is promising for relieving POLG disease and other severe conditions linked to depletion of mtDNA .
Target:
Cat. No.: HY-B0315A
Synonyms: Biotin-Cyanocobalamin B12
Target:
Target:
Target:
Research Areas:
Propanedial (Malondialdehyde) (13.88 mM in water) is one of the final products of lipid peroxidation. Propanedial causes protein inactivation, DNA damage and cross-linking by forming stable covalent adducts with biological macromolecules, which is the main mechanism for its cytotoxicity and genotoxicity.
Propanedial production increases with the elevation of free radicals.
Propanedial is a key biomarker for evaluating the level of cellular oxidative stress [1][2][3].
Cat. No.: HY-114293S
Purity: 97.40%
Synonyms: Acetyl-CoA-13C2 lithium
Research Areas:
Acetyl coenzyme A- 13C2 lithium is the 13C-labeled Acetyl coenzyme A (HY-114293). Acetyl-coenzyme A (Acetyl-CoA) is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A is also a key precursor of lipid synthesis .
Cat. No.: HY-P2096
CAS No.: 161258-30-6
Research Areas:
Cat. No.: HY-B0993
CAS No.: 140678-14-4
Synonyms: MnDPDP
Target:
Research Areas:
Mangafodipir trisodium (MnDPDP), hepatocellular-specific contrast agent, is an efficacious inhibitor of CIPN (chemotherapy-induced peripheral neuropath) and other conditions caused by cellular oxidative stress. Mangafodipir trisodium shows no negative interference with the tumoricidal activity of chemotherapy .
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Research Areas:
Glutamate dehydrogenase (NAD (P)) (GLDH) is a glutamate dehydrogenase . Glutamate dehydrogenase exists in all organisms and catalyzes the oxidative deamination of L-Glutamate (HY-W337739) to α-Ketoglutarate using NAD (P) + as a coenzyme. The glutamate dehydrogenase pathway is also associated with various cellular processes, including ammonia metabolism, acid-base balance, redox homeostasis, lipid biosynthesis, and lactate production .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
