63 Results for "

immunosuppressive agent

" in MedChemExpress (MCE) Product Catalog:
Products (63)

63 Results for "immunosuppressive agent" in MCE Product Catalog:

Cat. No.: HY-110044
CAS No.: 177653-76-8
Purity:  99.79%
Research Areas:  

Inflammation/Immunology

MNITMT is a more potent immunosuppressive agent without bone marrow toxicity .
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Cat. No.: HY-17420AR
CAS No.: 6055-19-2
Synonyms: Cyclophosphamide monohydrate (Standard)
Research Areas:  

Cancer

Cyclophosphamide (hydrate) (Standard) is the analytical standard of Cyclophosphamide (hydrate). This product is intended for research and analytical applications. Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.
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Cat. No.: HY-13677S1
CAS No.: 1190008-04-8
Purity:  ≥96.0%
Synonyms: Mercaptopurine-13C2,15N; 6-MP-13C2,15N
6-Mercaptopurine- 13C2, 15N is the 13C- and 15N-labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.
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Cat. No.: HY-B0214R
CAS No.: 53-03-2
Synonyms: Dehydrocortisone (Standard)
Prednisone (Standard) is the analytical standard of Prednisone. This product is intended for research and analytical applications. Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus .
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Cat. No.: HY-B0421R
CAS No.: 24280-93-1
Synonyms: Mycophenolate (Standard)
Mycophenolic acid (Standard) is the analytical standard of Mycophenolic acid. This product is intended for research and analytical applications. Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM.?Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects .
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Cat. No.: HY-16569R
CAS No.: 64-86-8
Colchicine (Standard) is the analytical standard of Colchicine. This product is intended for research and analytical applications. Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research .
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Cat. No.: HY-P10862
Target:  

Exosomes Virus Protease

Research Areas:  

Infection Cancer

AH-D peptide is a brain-penetrant antiviral agent disrupting highly curved lipid membranes. AH-D peptide exhibits broad-spectrum antiviral activity against ZIKV, Dengue virus, Chikungunya virus, yellow fever virus and Japanese encephalitis virus, with
IC50
values of 11.9, 12.5, 35.7, 206 and 136 nM, respectively. AH-D peptide reduces the viral load in the brain, suppresses inflammation, protects neurons, and does not damage the blood brain barrier. AH-D peptide restores antitumor immunity by decreasing circulating PD-L1 + exosomes, reducing intratumoral immunosuppressive cells (regulatory T cells, myeloid-derived suppressor cells), and enhancing T cell function. AH-D peptide inhibits membrane-enveloped viruses and cancer cell metastasis in vivo. AH-D peptide exhibits no immunogenicity and has negligible effects on normal tissues. AH-D peptide can be used for research in Zika virus and other mosquito-borne viruses, cancer immunotherapy and metastasis .
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Cat. No.: HY-13677AR
CAS No.: 6112-76-1
Synonyms: Mercaptopurine hydrate (Standard); 6-MP hydrate (Standard)
6-Mercaptopurine hydrate (Standard) is the analytical standard of 6-Mercaptopurine hydrate. This product is intended for research and analytical applications. 6-Mercaptopurine hydrate (Mercaptopurine hydrate; 6-MP hydrate) is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.
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Cat. No.: HY-B0256R
CAS No.: 446-86-6
Synonyms: BW 57-322 (Standard)
Azathioprine (Standard) is the analytical standard of Azathioprine. This product is intended for research and analytical applications. Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis .
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Cat. No.: HY-128747R
CAS No.: 56401-20-8
α-D-Glucose-1-phosphate disodium (Standard) is the analytical standard of α-D-Glucose-1-phosphate disodium (HY-128747). This product is intended for research and analytical applications. α-D-Glucose-1-phosphate disodium is used as a starting material for synthesis of glucuronic acid. α-D-Glucose-1-phosphate disodium can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiotic, as an immunosuppressive agent, and as a circulatory system therapy element.
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Cat. No.: HY-P99726
CAS No.: 127757-92-0

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Maslimomab is a murine monoclonal antibody targeting T-cell receptor. Maslimomab is an immunosuppressive agent .
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Cat. No.: HY-13677S
CAS No.: 82677-93-8
Synonyms: Mercaptopurine-d2; 6-MP-d2
6-Mercaptopurine-d2 is the deuterium labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent .
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Cat. No.: HY-P1355A
CAS No.: 286852-20-8
Target:  

Calcineurin Cyclophilin

Research Areas:  

Others

Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.
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Cat. No.: HY-P991543
CAS No.: 339181-10-1
Target:  

CD2

Research Areas:  

Inflammation/Immunology Cancer

BTI-322 is a human IgG1κ antibody directed against the CD2 antigen on T cells and NK cells. BTI-322 can block primary and memory alloantigen proliferative responses in vitro. BTI-322 recognizes over 90% of E-rosette-forming peripheral blood lymphocytes and T-cell leukemias. BTI-322 has immunosuppressive activity. BTI-322 effectively inhibits T cell responses in vitro to allogeneic cells. BTI-322 can be used as a T-cell deplting agent. BTI-322 can be studied in research for renal allograft rejection and steroid-refractory acute graft-versus-host disease .
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Cat. No.: HY-P1354
CAS No.: 156047-45-9
Target:  

Calcineurin Cyclophilin

Research Areas:  

Others

Cyclosporin A-Derivative 2 is a novel derivative from cyclosporin A. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.
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Cat. No.: HY-118047
CAS No.: 115787-68-3
CI 972 anhydrous is a potent, orally active, and competitive inhibitor of purine nucleoside phosphorylase (PNP) (Ki=0.83 μM) under development as a T cell-selective immunosuppressive agent .
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Cat. No.: HY-P1355
CAS No.: 1487360-85-9
Target:  

Calcineurin Cyclophilin

Research Areas:  

Inflammation/Immunology

Cyclosporin A-Derivative 1 is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.
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Cat. No.: HY-B0214S2
Synonyms: Dehydrocortisone-d4
Prednisone-d4 is deuterated labeled Prednisone (HY-B0214). Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus .
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Cat. No.: HY-13677R
CAS No.: 50-44-2
Synonyms: Mercaptopurine (Standard); 6-MP (Standard)
6-Mercaptopurine (Standard) is the analytical standard of 6-Mercaptopurine. This product is intended for research and analytical applications. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive drug.
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Cat. No.: HY-107338
CAS No.: 51287-57-1
Synonyms: Vratizolin; Wratizolin
Denotivir (Vratizolin) is an orally active antiviral agent for herpes simplex virus (HSV) and varicella-zoster virus (VZV). Denotivir inhibits the proliferation of various cancer cells, and exhibits anti-leukemic activity. Denotivir inhibits the generation of TNF-α, IL-1 and IL-6, exhibits immunosuppressive efficacy .
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