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  2. Cyclosporin A-Derivative 1 Free base

Cyclosporin A-Derivative 1 Free base 

Cat. No.: HY-P1355A Purity: 99.29%
Handling Instructions

Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Cyclosporin A-Derivative 1 Free base Chemical Structure

Cyclosporin A-Derivative 1 Free base Chemical Structure

CAS No. : 286852-20-8

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10 mM * 1 mL in DMSO USD 983 In-stock
Estimated Time of Arrival: December 31
1 mg USD 150 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
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Description

Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.

In Vitro

Cyclosporin A-Derivative 1 is a non-immunosuppressive Cyclosporin A derivative. The cyclosporin is acylated on the butenyl-methyl-threonine side chain and then subjected to a ring-opening reaction (the ring opens between the sarcosine and the N-methyl-leucine residues). Cyclosporin A-Derivative 1 is a linear peptide intermediate[1].

Molecular Weight

1276.69

Formula

C₆₅H₁₁₇N₁₁O₁₄

CAS No.

286852-20-8

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
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Product Name:
Cyclosporin A-Derivative 1 Free base
Cat. No.:
HY-P1355A
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