31 Results for "

monocytic

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "monocytic" in MCE Product Catalog:

Cat. No.: HY-19619R
CAS No.: 200933-14-8
Target:  

Phospholipase Apoptosis

Research Areas:  

Cancer

m-3M3FBS (Standard) is the analytical standard of m-3M3FBS. This product is intended for research and analytical applications. m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, upregulates intracellular calcium concentration, and stimulates inositol phosphate generation in various cell lines. m-3M3FBS induces monocytic leukemia cell apoptosis .
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Cat. No.: HY-181048
Target:  

Casein Kinase MDM-2/p53

Research Areas:  

Cancer

CK1α-IN-1 (Compound 7a) is a selective CK1α inhibitor with an IC50 of 10.96 nM. CK1α-IN-1 dose-dependently stabilizes p53 protein. CK1α-IN-1 has anticancer activity against acute monocytic leukemia .
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Cat. No.: HY-184882
CAS No.: 2771021-30-6
Research Areas:  

Inflammation/Immunology Cancer

NLRP3-IN-95 is an NLRP3 inflammasome inhibitor with an IC50 of 27 nM. NLRP3-IN-95 inhibits IL-1β secretion in PMA-differentiated THP-1 cells. NLRP3-IN-95 can be used in studies related to acute monocytic leukemia and inflammatory diseases .
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Cat. No.: HY-W409652
CAS No.: 2101206-26-0
Target:  

CDK EGFR HDAC

Research Areas:  

Cancer

CLK1/4-IN-2 is a selective CLK1/4 inhibitor, with an IC50 of 7 nM against CLK1 and an IC50 of 2.3 nM against CLK4. CLK1/4-IN-2 induces protein depletion in cancer cells and exhibits anticancer activity. CLK1/4-IN-2 can be used in research related to breast cancer, monocytic leukemia, bladder cancer, mammary adenocarcinoma and hepatocellular carcinoma .
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Cat. No.: HY-180150
Research Areas:  

Cancer

PROTAC BRD4 Degrader-42 (Compound P6) is a PROTAC-based BRD4 degrader with a DC50 of 1.11 μM. PROTAC BRD4 Degrader-42 promotes the ubiquitination and degradation of BRD4. PROTAC BRD4 Degrader-42 downregulates c-Myc expression and induces Apoptosis by upregulating BAD and BAX protein expression. PROTAC BRD4 Degrader-42 also exhibits anticancer activity against myeloid monocytic leukemia .
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Cat. No.: HY-W724097
CAS No.: 84746-00-9
Target:  

PKC TRP Channel Apoptosis

Research Areas:  

Metabolic Disease Cancer

1-Oleoyl-2-acetylglycerol is a membrane-permeable diacylglycerol analog and PKC activator. 1-Oleoyl-2-acetylglycerol activates TRPC3 channels. 1-Oleoyl-2-acetylglycerol attenuates D609 (HY-70072)-induced Apoptosis. 1-Oleoyl-2-acetylglycerol effectively stimulates insulin secretion . 1-Oleoyl-2-acetylglycerol can be used in research on monocytic leukemia .
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Cat. No.: HY-W714933
CAS No.: 78362-05-7
Synonyms: (4,8)-(+)-Gallocatechin-(+)-catechin
Target:  

Caspase Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Prodelphinidin B3 is a proanthocyanidin compound that exhibits significant anti-tumor activity. Prodelphinidin B3 induces cell cycle arrest at the G1/G0 phase in PC-3 cells, activates caspase-3, and promotes apoptosis. Prodelphinidin B3 can induce the differentiation of leukemia cells and synergistically enhance retinoic acid (HY-14649)-induced granulocytic differentiation and sodium butyrate (HY-B0350A)-induced monocytic differentiation in HL-60 cells. Prodelphinidin B3 also possesses antioxidant activity. Prodelphinidin B3 is used in research on prostate cancer and leukemia .
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Cat. No.: HY-N20639
CAS No.: 464-71-1
Synonyms: 3-Deoxycaryoptinol
Clerodin (3-Deoxycaryoptinol) is a natural diterpenoid compound that can be isolated from traditional Chinese medicinal plants such as Clerodendrum infortunatum. Clerodin exhibits caspase-3 regulation, apoptosis induction, cell cycle arrest, ROS induction and glutathione depletion effects, along with anti-cancer and antifeedant activities. It shows selective cytotoxicity against leukemia cells and breast cancer cells, but has no obvious toxicity to normal human blood cells and lymphocytes. Clerodin also reduces the feeding behavior of Helicoverpa armigera larvae on cabbage leaf discs, but has no significant contact toxicity to these larvae. Clerodin can be used in research related to acute monocytic leukemia and human breast cancer .
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Cat. No.: HY-P704206
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KAT6B; K(Lysine) Acetyltransferase 6B; Prev. MYST4; MOZ-Related Factor; MOZ2; ZC2HC6B; Querkopf; MYST-4; Morf; Histone Acetyltransferase MYST4; Qkf; Histone Acetyltransferase MORF; MYST Histone Acetyltransferase (monocytic Leukemia) 4; Histone Acetyltrans
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P86929A
Synonyms: Histone acetyltransferase KAT6A EC:2.3.1.48 MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3 (MYST-3) monocytic leukemia zinc finger protein Runt-related transcription factor-binding protein 2 Zinc finger protein 220 KAT6A MOZ MYST3 RUNXBP2 Histone acetyltransferase KAT6A EC:2.3.1.48 MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3 (MYST-3) monocytic leukemia zinc finger protein Runt-related transcription factor-binding protein 2 Zinc finger protein 220 KAT6A MOZ MYST3 RUNXBP2 ZNF220

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC, ChIP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P703234
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KAT6A; Histone Acetyltransferase KAT6A; Prev. MYST3; Zinc Finger Protein 220; Prev. RUNXBP2; ZC2HC6A; Prev. ZNF220; MYST-3; MOZ; Runt-Related Transcription Factor-Binding Protein 2; monocytic Leukemia Zinc Finger Protein; Histone Acetyltransferase MYST3;
Species:  
Human
Source:  
E. coli
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