197 Results for "

Cancer therapy

" in MedChemExpress (MCE) Product Catalog:
Products (197)

197 Results for "Cancer therapy" in MCE Product Catalog:

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Cat. No.: HY-P990059
CAS No.: 2760250-47-1
Synonyms: INT-016; AZD8205 Antibody

Research Areas:  

Cancer

Puxitatug (INT-016; AZD8205 Antibody) is a monoclonal antibody targeting VTCN1/B7-H4. Puxitatug can be used to synthesize antibody-drug conjugates (ADCs), such as Puxitatug samrotecan (HY-171689), which can be applied to various solid tumors. Puxitatug can also be used for researching adjuvant therapies for gastric cancer .
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Cat. No.: HY-164165
CAS No.: 245110-80-9
Research Areas:  

Cancer

Paclitaxel-2′-succinate NHS ester is a Paclitaxel (HY-B0015) derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy .
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Cat. No.: HY-169903
CAS No.: 1189710-20-0
Target:  

Apoptosis

Research Areas:  

Cancer

SMIP34 is a PELP1 inhibitor. SMIP34 binds to PELP1 with a Kd of 37.4 μM. SMIP34 inhibits cancer cell proliferation and tumor progression. SMIP34 can be used for breast cancer research, and is active against wild-type (WT), mutant (MT) ER+ and therapy-resistant (TR)-ER+ breast cancer .
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Cat. No.: HY-151168
CAS No.: 32744-80-2
Purity:  99.70%
Research Areas:  

Inflammation/Immunology Cancer

3-Chlorogentisyl alcohol is a potent E. coli β-glucuronidase inhibitor with an IC50 value of 0.74 μM, an Ki value of 0.58 μM. 3-Chlorogentisyl alcohol shows antiproliferative activity. 3-Chlorogentisyl alcohol has the potential for the research of anti-cancer and anti-inflammatory therapies .
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Cat. No.: HY-W440886
Target:  

Liposome

Research Areas:  

Others

DSPE-PEG3400-Biotin is a phospholipid PEG for biotinylation. The amphiphilic property of the DSPE-PEG is useful for precision drug delivery and cancer therapy.
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Cat. No.: HY-155798
CAS No.: 2871057-47-3
Research Areas:  

Cancer

BBI-2779 is a highly selective, orally active CHK1 inhibitor with a CHK1 IC50 of 0.3 nM. BBI-2779 leverages transcription-replication conflicts on extrachromosomal DNA (ecDNA) to induce synthetic lethality, replication stress, DNA damage and cell death in ecDNA-positive tumor cells. BBI-2779 blocks ecDNA-mediated acquired resistance to targeted therapies and inhibits tumor growth in mouse models of gastric cancer. BBI-2779 is applicable to ecDNA-positive cancer-related research .
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Cat. No.: HY-175673
CAS No.: 2211175-99-2
LCB-2151 (Compound 2), a nucleoside analogue, is an anticancer agent. LCB-2151 disrupts the two primary sources of ATP production (glycolysis and mitochondrial oxidative phosphorylation), reducing the bioenergetic capacity of KRAS-mutated pancreatic cancer cells and inducing ROS formation. LCB-2151 effectively inhibits key enzymes (such as CACT and CPT2) in glycolysis, the TCA cycle and fatty acid β-oxidation. LCB-2151 has significant cytotoxicity and induces cells apoptosis. LCB-2151 can be used for radiation therapy of cancers research .
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Cat. No.: HY-175744
CAS No.: 3077205-52-5
Target:  

PSMA

Research Areas:  

Cancer

PSMA-MAL-5 is a PSMA ligand. PSMA-MAL-5 covalently binds to Cys466 of PSMA. PSMA-MAL-5 labeled with 177Lu and 225Ac has high radiostability and tumor uptake. PSMA-MAL-5 also effectively inhibits tumor growth. PSMA-MAL-5 can be used for SPECT/CT imaging and radionuclide therapy of prostate cancer .
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Cat. No.: HY-137474
CAS No.: 51744-55-9
Purpurin 18 methyl ester, a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT). Purpurin 18 methyl ester has photodynamic activity to induce cancer cell death .
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Cat. No.: HY-W040270
CAS No.: 928292-69-7
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Amino-PEG10-amine, a PEG-based PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer .
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Cat. No.: HY-175685
CAS No.: 3020777-28-7
Target:  

FAP

Research Areas:  

Cancer

FAP-IN-7 (Compound 5b) is a FAPtherapy of cancers research .
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Cat. No.: HY-161795
Target:  

Drug Metabolite

Research Areas:  

Cancer

SP3CHO is an active metabolite generated by the metabolism of SP3N in cell culture by the action of amine oxidase. SP3CHO can induce polyubiquitination of specific proteins by recruiting the SCFFBXO22 E3 ligase complex. SP3CHO can be used in cancer therapy research .
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Cat. No.: HY-156290
CAS No.: 3053678-30-8
Target:  

STING

Research Areas:  

Inflammation/Immunology Cancer

SAP-04 is a potent and orally active STING agonist. SAP-04 exhibits potent immunomodulatory effects for cancer therapy .
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Cat. No.: HY-149664
CAS No.: 137056-72-5
Synonyms: DC-Chol
Target:  

Liposome

Research Areas:  

Cancer

3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol, a lipid, has been investigated in cancer gene therapy and vaccine delivery system .
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Cat. No.: HY-16488R
CAS No.: 122341-38-2
Synonyms: m-THPC (Standard); KW2345 (Standard)
Research Areas:  

Cancer

Temoporfin (Standard) is the analytical standard of Temoporfin. This product is intended for research and analytical applications. Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers .
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Cat. No.: HY-130411
CAS No.: 479200-82-3
Purity:  ≥95.0%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer .
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Cat. No.: HY-W738979
CAS No.: 92396-91-3
Target:  

Photosensitizer

Silicon naphthalocyanine dichloride is a photosensitizer with potential anti-tumor activity. Silicon naphthalocyanine dichloride is used as a cancer-inhibiting compound in photodynamic therapy. Silicon naphthalocyanine dichloride can effectively absorb light energy of a specific wavelength, thereby generating oxygen free radicals that help destroy cancer cells. The biocompatibility of Silicon naphthalocyanine dichloride makes it show good prospects in medical applications.
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Cat. No.: HY-145268
CAS No.: 863761-17-5
Target:  

Cadherin

Research Areas:  

Cancer

SLEC-11 is a CDH1/E-cadherin modulator that potently inhibits cell death in E-cadherin-deficient cells (EC50=8.2 μM). SLEC-11 can be used to study potential synthetic lethal therapies for gastric cancer .
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Cat. No.: HY-137473R
CAS No.: 6453-67-4
Synonyms: Pyropheophorbide-a methyl ester (Standard)
Research Areas:  

Cancer

Methyl pyropheophorbide-a (Standard) is the analytical standard of Methyl pyropheophorbide-a. This product is intended for research and analytical applications. Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide-a has photodynamic activity and can induce apoptosis and inhibit tumor growth .
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Cat. No.: HY-113011R
CAS No.: 1109-28-0
Maltotriose (Standard) is the analytical standard of Maltotriose (HY-13011). This product is intended for research and analytical applications. Maltotriose is a maltooligosaccharide and a specific inducer of the Escherichia coli maltose operon. The oligosaccharide structure of Maltotriose acts as a highly efficient drug delivery carrier, which significantly enhances the targeting ability and water solubility of photosensitizers in photodynamic therapy for pancreatic cancer.
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