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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
131 Results for "
IL13
" in MedChemExpress (MCE) Product Catalog:
Products (131)
131 Results for "IL13" in MCE Product Catalog:
Cat. No.: HY-P990741
CAS No.: 2648456-30-6
Synonyms: UCB-9741
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Chitinase, Serratia marcescens is a chitinase from Serratia marcescens. Chitinase is a chitin-targeting enzyme with chitin hydrolysis activity. Chitinase inhibits chitin-induced innate type 2 inflammation in the lung. Chitinase augments chitin-free, allergen-induced Th2 inflammation. Chitinase mediates effector functions of IL-13 .
Cat. No.: HY-P990699
CAS No.: 2641479-65-2
Synonyms: ZTS-00008183
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Cat. No.: HY-P99883
CAS No.: 1399584-78-1
Synonyms: SAR156597
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Chitinase is a chitin-targeting enzyme with chitin hydrolysis activity. Chitinase inhibits chitin-induced innate type 2 inflammation in the lung. Chitinase augments chitin-free, allergen-induced Th2 inflammation. Chitinase mediates effector functions of IL-13 .
Cat. No.: HY-P99870
CAS No.: 2445460-16-0
Synonyms: ASLAN004; CSL-334; MK-6105
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Eblasakimab (ASLAN004) is a fully human monoclonal antibody that binds with high affinity to IL-13Rα1 (binds to IL-13Rα1 with a Kd of 453 pM). Eblasakimab reduces neuronal responses to IL-4, IL-13, and their combination . Eblasakimab can be used in research on atopic dermatitis .
Cat. No.: HY-110295
CAS No.: 688347-51-5
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SPL-334 is a potent and selective S-Nitrosoglutathione reductase (GSNOR) inhibitor. SPL-334 causes a significant reduction in the production of Th2 cytokines IL-5 and IL-13 and the levels of the chemokine CCL11 (eotaxin-1) in the airways. SPL-334 can be used in research of allergic airway inflammation .
Cat. No.: HY-144683A
CAS No.: 2415317-57-4
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PF-07038124 hydrochloride is a PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2. PF-07038124 hydrochloride shows inhibitory activities against IL-13, IL4, and IFNγ (IC50=125, 4.1, 1.06 nM, respectively). PF-07038124 hydrochloride can be used for research of atopic dermatitis and plaque psoriasis .
Cat. No.: HY-P99417
CAS No.: 2043952-59-4
Synonyms: UCB4144; VR 942
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Cat. No.: HY-162248
CAS No.: 3023876-01-6
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JAK1/2-IN-1 is a potent JAK1 and JAK2 inhibitor with IC50 values of 0.4 nM and 8.1 nM, respectively. JAK1/2-IN-1 also inhibits IL-4 and IL-13 with IC50s of 136.5 nM and 19.1 nM, respectively (WO2023244775A1; Example 33a) .
Cat. No.: HY-144683
CAS No.: 2415085-44-6
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PF-07038124 is a PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2. PF-07038124 shows inhibitory activities against IL-13, IL4, and IFNγ (IC50=125, 4.1, 1.06 nM, respectively). PF-07038124 can be used for research of atopic dermatitis and plaque psoriasis .
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iJak-381 is a JAK1/2 inhibitor with anti-inflammatory activity. iJak-381 blocks IL-13 signaling and also inhibits IL-4 and IL-6 signaling pathways. iJak-381 also reduced p-STAT6 levels and inhibited the influx of inflammatory cells into the lungs of mice. iJak-381 inhibits airway hyperresponsiveness (AHR) .
Cat. No.: HY-RS06686
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Il13 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il13 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS06685
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IL13 Human Pre-designed siRNA Set A contains three designed siRNAs for IL13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-174639
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Human IL13 mRNA encodes the human interleukin 13 (IL13) protein, an immunoregulatory cytokine produced primarily by activated Th2 cells. IL13 is involved in several stages of B-cell maturation and differentiation and is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.
Cat. No.: HY-P991150
CAS No.: 2981477-39-6
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Cat. No.: HY-P991258
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Cat. No.: HY-RS06687
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Il13 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il13 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P991633
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Cat. No.: HY-P11147
CAS No.: 2319573-67-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
