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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
71 Results for "
IM
" in MedChemExpress (MCE) Product Catalog:
Products (71)
71 Results for "IM" in MCE Product Catalog:
Target:
Research Areas:
TKIM is a TREK-1 channel inhibitor with an IC50 of 2.96 μM. TKIM binds to the pocket of the intermediate (IM) state of TREK-1 .
Cat. No.: HY-12292R
CAS No.: 1129669-05-1
IM-12 (Standard) is the analytical standard of IM-12. This product is intended for research and analytical applications. IM-12 is an inhibitor of GSK-3β, with an IC50 of 53 nM, and also enhances Wnt signalling.
Cat. No.: HY-130959
CAS No.: 1032072-50-6
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Tubulysin IM-2 is a microtubule/Tubulin inhibitor that can act as an ADC cytotoxin (ADC Cytotoxin) and an anti-microtubule toxin (anti-microtubule toxins). Used for ADC synthesis.
Cat. No.: HY-130960
CAS No.: 1639986-05-2
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Tubulysin IM-3 is a microtubule/Tubulin inhibitor that can act as an ADC cytotoxin (ADC Cytotoxin) and an anti-microtubule toxin (anti-microtubule toxins). Used for ADC synthesis.
Cat. No.: HY-130958
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Tubulysin IM-1 is a microtubule/Tubulin inhibitor that can act as an ADC cytotoxin (ADC Cytotoxin) and an anti-microtubule toxin (anti-microtubule toxins). Used for ADC synthesis .
Cat. No.: HY-W142171
CAS No.: 109434-24-4
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Cat. No.: HY-160577
CAS No.: 2758097-38-8
DOG-IM4 can be used to synthesize nanoparticles to deliver antigen-encoding nucleic acids. It could be used to try to target autoimmune diseases, rare blood or metabolic diseases, allergies, cancer or infectious diseases .
Cat. No.: HY-125283A
CAS No.: 1544871-16-0
Synonyms: 2-Me-Phen; 2-Me-Phenformin
Research Areas:
IM176OUT05 free base (2-Me-Phen), a biguanide, is a mitochondrial OXPHOS inhibitor. IM176OUT0 free base inhibits mitochondrial electron transport chain (ETC) activity with an IC50 of 3.2 μM. IM176OUT05 free base activates stem cell metabolism, promotes hair regrowth and increases stemness induction and maintenance during the pluripotent stem cell generation process .
Cat. No.: HY-160714
CAS No.: 3002986-41-3
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Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH (IM-3) is a cleavable ADC linker that can be used for the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-10049A
CAS No.: 145877-52-7
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CP 122721 hydrochloride is a potent, non-peptide and selective nonpeptide neurokinin NK1 antagonist, with a pIC50 of 9.8 for human NK1 receptor expressed in IM-9 cells. CP 122721 hydrochloride exhibits anxiolytic and antidepressant-like effects .
Cat. No.: HY-P991462
Cat. No.: HY-149697
CAS No.: 1699760-76-3
Insecticidal agent 6 (Compound Im) is an insect ryanodine receptors (RyRs) inhibitor, with an EC50 value of 0.6308 µM against S. frugiperda RyRs. Insecticidal agent 6 has excellent insecticidal activity against lepidopteran pests and can be used for research on pests and diseases .
Cat. No.: HY-W020468R
CAS No.: 105431-72-9
Synonyms: DuP 996 (Standard)
Research Areas:
Linopirdine (DuP 996) is an orally active, selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor with an IC50 of 2.4 μM. Linopirdine is a TRPV1 agonist. Linopirdine, a putative cognition enhancing agent, increases acetylcholine release in rat brain tissue .
Cat. No.: HY-108351R
CAS No.: 861891-50-1
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IM-54 (Standard) is the analytical standard of IM-54 (HY-108351). This product is intended for research and analytical applications. IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death .
Cat. No.: HY-12292G
CAS No.: 1129669-05-1
Cat. No.: HY-187183
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IM-07 is a 12-lipoxygenase (ALOX12) ligand that can be used for the synthesis of PROTACs, such as MH-06 (HY-187182) .
Cat. No.: HY-178557
CAS No.: 1005791-93-4
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Im-3'-OMe-GMP is a monomeric raw material that can be used for nucleic acid synthesis.
Cat. No.: HY-P992220
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
