TKIM
Based on 1 Customer Validation
TKIM is a TREK-1 channel inhibitor with an IC50 of 2.96 μM. TKIM binds to the pocket of the intermediate (IM) state of TREK-1.
For research use only. We do not sell to patients.
- Purity: 99.73%
- CAS No.: 326921-25-9
- Formula: C18H14ClN3O2S
- Molecular Weight:371.84
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 326921-25-9
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Appearance Solid
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Molecular Weight 371.84
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Formula C18H14ClN3O2S
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Color Off-white to light yellow
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SMILES
O=C(NNC(CSC1=NC2=CC=CC=C2C=C1)=O)C3=CC=C(Cl)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (672.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6893 mL | 13.4466 mL | 26.8933 mL | 67.2332 mL |
| 5 mM | 0.5379 mL | 2.6893 mL | 5.3787 mL | 13.4466 mL | |
| 10 mM | 0.2689 mL | 1.3447 mL | 2.6893 mL | 6.7233 mL | |
| 15 mM | 0.1793 mL | 0.8964 mL | 1.7929 mL | 4.4822 mL | |
| 20 mM | 0.1345 mL | 0.6723 mL | 1.3447 mL | 3.3617 mL | |
| 25 mM | 0.1076 mL | 0.5379 mL | 1.0757 mL | 2.6893 mL | |
| 30 mM | 0.0896 mL | 0.4482 mL | 0.8964 mL | 2.2411 mL | |
| 40 mM | 0.0672 mL | 0.3362 mL | 0.6723 mL | 1.6808 mL | |
| 50 mM | 0.0538 mL | 0.2689 mL | 0.5379 mL | 1.3447 mL | |
| 60 mM | 0.0448 mL | 0.2241 mL | 0.4482 mL | 1.1206 mL | |
| 80 mM | 0.0336 mL | 0.1681 mL | 0.3362 mL | 0.8404 mL | |
| 100 mM | 0.0269 mL | 0.1345 mL | 0.2689 mL | 0.6723 mL |
TKIM Related Classifications
HY-134559 Related Classifications
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