172 Results for "

simplex

" in MedChemExpress (MCE) Product Catalog:
Products (172)

172 Results for "simplex" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P70494
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NECTIN1; OFC7; Prev. PVRL1; Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C); Prev. HVEC; Herpesvirus Ig-Like Receptor; Prev. ED4; Ectodermal Dysplasia 4 (Margarita Island Type); Nectin-1; Herpes simplex Virus Type 1 Sensitivity; PRR1; Herpesv
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-168034
CAS No.: 2138299-65-5
diABZI-4 is a STING activator and broad-spectrum antiviral agent with immunostimulatory activity. diABZI-4 triggers the TBK1-IRF3 and NF-κB signaling cascades by inducing STING oligomerization, thereby promoting the production of type I/III interferons and various proinflammatory cytokines. diABZI-4 exhibits broad-spectrum antiviral activity and effectively inhibits the replication of influenza A virus, SARS-CoV-2, herpes simplex virus, and other viruses. diABZI-4 also activates lymphocytes and macrophages to provide significant pre- and post-exposure protection in viral disease models. diABZI-4 can be used to study COVID-19, respiratory viral infections, and related immunopathological mechanisms .
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1
1 Cited Publications
Cat. No.: HY-N0093
CAS No.: 10212-25-6
Synonyms: Cyclocytidine hydrochloride; Cyclo-CMP hydrochloride; Cyclo-C
Ancitabine (Cyclocytidine) hydrochloride is a cytarabine derivative that inhibits viral replication. Ancitabine hydrochloride blocks vaccinia virus DNA replication, the progression of viral protein synthesis from early to late stages, and one-step growth of vaccinia virus. Ancitabine hydrochloride is applicable to research related to vaccinia virus infection, leukemia, human cytomegalovirus infection and colorectal cancer .
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Cat. No.: HY-113431
CAS No.: 7013-16-3
Purity:  ≥99.0%
Arabinosylhypoxanthine is a purine nucleoside analog. Arabinosylhypoxanthine selectively inhibits viral DNA synthesis. Arabinosylhypoxanthine exhibits anti-HSV activity. Arabinosylhypoxanthine can be used in studies related to herpes simplex virus infection .
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Cat. No.: HY-B1011
CAS No.: 15176-29-1
Synonyms: EUDR
Target:  

Virus Protease

Research Areas:  

Infection

Edoxudine is an antiviral active molecule and thymidine analog. Edoxudine is effective against herpes simplex virus .
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Cat. No.: HY-W291131
CAS No.: 27830-79-1
Synonyms: IBT
Target:  

HSV Orthopoxvirus

Research Areas:  

Infection

Isatin-β-thiosemicarbazone is a potent anti-poxvirus agent (including monkeypox virus, orthopoxvirus, vaccinia virus, etc). Isatin-β-thiosemicarbazone also is a potent herpes simplex virus (HSV) inhibitor. Isatin-β-thiosemicarbazone exhibits
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Cat. No.: HY-131944
CAS No.: 3054-47-5
Purity:  ≥96.0%
Target:  

Apoptosis HSV

S-Acetylglutathione is a glutathione derivative and intracellular glutathione supplement that bypasses glutathione synthetase deficiency through intracellular thioesterase conversion, exhibits higher blood stability than glutathione, and selectively induces apoptosis in lymphoma and malignant cells by inducing oxidative stress (apoptosis). S-Acetylglutathione can be used in research on glutathione synthetase deficiency, herpes simplex virus type 1 infection, murine AIDS, lymphoma, and malignant tumors .
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Cat. No.: HY-N1060
CAS No.: 40456-50-6
Yatein is a lignan isolated from A. chilensis, with antiproliferative activity . Yatein suppresses herpes simplex virus type 1 (HSV-1 ) replication by interruption the immediate-early gene expression .
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Cat. No.: HY-N3395
CAS No.: 152464-78-3
Leachianone G is an antiviral flavonoid from the root bark of Morus alba L. Leachianone G shows potent antiviral activity against herpes simplex type 1 virus (HSV-1) with an IC50 value of 1.6 μg/mL .
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Cat. No.: HY-17425AR
CAS No.: 124832-27-5
Synonyms: Valaciclovir hydrochloride (Standard)
Research Areas:  

Infection Cancer

Valacyclovir (hydrochloride) (Standard) is the analytical standard of Valacyclovir (hydrochloride). This product is intended for research and analytical applications. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422) .
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Cat. No.: HY-P5997
CAS No.: 2104728-28-9
XQ2B is a specific cGAS inhibitor targeting protein-DNA interaction and phase separation. XQ2B markedly reduces ISD-induced Autophagy. XQ2B inhibits herpes simplex virus 1 (HSV-1)-induced antiviral immune responses and enhances HSV-1 infection .
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Cat. No.: HY-106892
CAS No.: 127142-14-7
Purity:  99.62%
Synonyms: 348U87
Target:  

DNA/RNA Synthesis

Research Areas:  

Infection

BW 348U87 is an inhibitor for ribonucleotide reductase, which exhibits synergistic effect with Acyclovir (HY-17422), potentiate the antiviral activity of Acyclovir against herpes simplex virus (HSV) in athymic nude mouse model .
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Cat. No.: HY-W353804
CAS No.: 31501-19-6
Research Areas:  

Infection

2'-Deoxy-β-L-uridine is a nucledside analogue and a specific substrate for the viral enzyme, shows no stereospecificity against herpes simplex 1 (HSV1) thymidine kinase (TK). 2′-Deoxy-β-L-uridine exerts antiviral activity via the interation of 5'-triphosphates with the viral DNA polymerase .
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Cat. No.: HY-P10868
CAS No.: 2056232-82-5
Synonyms: RLS-0071
Pegtarazimod (RLS-0071) is a dual-target anti-inflammatory peptide that exerts its effects by simultaneously regulating the complement system and neutrophil-associated inflammatory pathways. Pegtarazimod reduces ROS production both in vitro and in vivo, and decreases the level of neutrophil elastase, a marker of neutrophil extracellular traps (NETs), in vivo, thereby alleviating inflammatory responses. Pegtarazimod significantly improves the survival rate of mice in multiple in vivo models of acute graft-versus-host disease (aGVHD). Pegtarazimod inhibits the activation of the C1 complex, reduces the herpes zoster-like spread of herpes simplex virus type 1 skin infection, and improves the survival rate of infected mice . Pegtarazimod can be used in research related to acute graft-versus-host disease, acute pulmonary diseases, and skin herpes simplex virus type 1 infection .
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Cat. No.: HY-P10153
CAS No.: 1360823-60-4
Target:  

Inhibitory Antibodies

Research Areas:  

Others

gH625 is a cell-penetrating viral peptide which is a part of glycoprotein H of Herpes simplex virus type I. gH625 is able to cross the cell membrane and to transport many conjugated cargoes into the cytosol. gH625 is permeable to the blood-brain barrier (BBB) and can enter the rat brain in vivo without toxic effects. gH625 can be used for siRNA delivery research .
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Cat. No.: HY-W002008
CAS No.: 480-68-2
Target:  

HSV

Research Areas:  

Infection Inflammation/Immunology

5-Nitrobarbituric acid is a herpes simplex virus type-1 (HSV-1) inhibitor (IC50=1.7 μM) .
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Cat. No.: HY-114247
CAS No.: 69256-17-3
Synonyms: D-FMAU
Research Areas:  

Infection Cancer

FMAU is a nucleoside analog and cell proliferation marker that can be phosphorylated by human thymidine kinase and subsequently incorporated into DNA. FMAU is applicable to research related to herpes simplex virus infection, various cancers, hepatitis B virus infection, and Epstein-Barr virus infection .
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Cat. No.: HY-129861
CAS No.: 69075-47-4
Target:  

HSV

Research Areas:  

Infection Cancer

5'-Ethynyl-2'-deoxycytidine is an inhibitor for HSV, that inhibits the cytopathic effect of HSV-1 in primary rabbit kidney cell with a MIC of 0.2 μg/mL. 5'-Ethynyl-2'-deoxycytidine inhibits the proliferation of leukemia L1210 cell with an IC50 of 64.5 μg/mL .
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Cat. No.: HY-17422B
CAS No.: 66341-16-0
Research Areas:  

Infection Cancer

Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agent. Acyclovir monophosphate blocks DNA synthesis through the inhibition of the viral DNA polymerase and terminates the chain elongation of the viral DNA. Acyclovir monophosphate shows antitumor activity .
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Cat. No.: HY-N9522
CAS No.: 51161-58-1
β-D-glucopyranosyl-[α-L-rhamnopyranosyl-(1→3)-βD-glucuronopyranosyl-(1→3)]-3β-hydroxyolean-12-ene28-oate, as a saponin, has a glucuronic acid attached to carbon C-3 and is isolated from S. simplex .
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